Results 171 to 180 of about 4,048,647 (310)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Developing the PATH-GP (Prevention and Testing for HIV in General Practice) intervention: a person-based approach intervention development study to increase HIV testing and PrEP access. [PDF]

Br J Gen Pract
Scott A, Family H, Horwood J, Saunders J, Sullivan A, Burgin J, Harryman L, Stockwell S, Copping J, Sheehan P, Macleod J, Dawson S, Kesten JM, Denford S.   +13 more
europepmc   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Similarities and important distinctions between drug and behavioral intervention development. [PDF]

Discov Psychol
Fisher HM, Winger JG, Samsa GP, Somers TJ.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

How can we improve migrant health checks in UK primary care: 'Health Catch-UP!' a protocol for a participatory intervention development study. [PDF]

BMJ Open
Carter J, Knights F, Mackey K, Deal A, Hassan E, Trueba J, Jayawardhena N, Alfred J, Al-Sharabi I, Ciftci Y, Aspray N, Harris P, Jayakumar S, Seedat F, Sanchez-Clemente N, Hall R, Majeed A, Harris T, Requena Méndez A, Zenner D, Tonkin-Crine S, Hargreaves S.   +21 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

A digital health intervention: development and validation of a social media nursing program for sexual dysfunction following cervical cancer radical hysterectomy. [PDF]

Front Public Health
Huang C, Qiu Y, Huang X, Tang H.
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Education and Music Intervention to Reduce Anxiety (EMIRA) in cardiac catheterization: intervention development. [PDF]

Pilot Feasibility Stud
de Carvalho Batista L, de Góes Salvetti M, de Cassia Gengo E Silva Butcher R.   +2 more
europepmc   +1 more source