Results 201 to 210 of about 4,048,647 (310)

Conceptual Model of and Intervention Development for Unplanned Suicide Attempts. [PDF]

Perm J
Whiteside U, Angerhofer Richards J, Fruhbauerova M, Shokouhaghaei G.   +3 more
europepmc   +1 more source

DEVELOPMENTS IN CLINICAL INTERVENTIONS [PDF]

The Gerontologist, 2016
openaire   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A clinical nomogram for predicting major adverse cardiovascular and cerebrovascular events in elderly Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention: development and validation in a real-world cohort. [PDF]

J Geriatr Cardiol
Xu JJ, Li QX, Yuan DS, Wang PZ, Hao YC, Zhu P, Song Y, Yao Y, Jiang L, Wang JY, Zhao XY, Song L, Yuan JQ, Zhang Y.   +13 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Formative Study to Inform a Physical Activity Intervention Targeted to Rural Men in the United States

Health Science Reports
Jacob Gallagher, Emine O. Bayman, Lisa A. Cadmus‐Bertram, Nathaniel D. M. Jenkins, Amy Pearlman, Kara M. Whitaker, Lucas J. Carr   +6 more
doaj   +1 more source

A new role profile for nurses with expanded competencies promoting person-centered care in long-term care: a mixed-methods intervention development study. [PDF]

BMC Geriatr
Silies K, Huckle T, Pohontsch N, Jarchow AM, Schütz K, Müller M, Lühmann D, Balzer K.   +7 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Model-informed precision dosing of vancomycin in clinical practice: an intervention development study. [PDF]

Int J Clin Pharm
Swartling M, Hamberg AK, Furebring M, Tängdén T, Nielsen EI.   +4 more
europepmc   +1 more source