Results 81 to 90 of about 4,048,647 (310)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Talking Points Tool: A Brief Intervention to Support Predoctoral Student and Faculty Advisor Communication [PDF]

open access: yes, 2019
Excellent relationships between predoctoral students and faculty supervisors can lay the foundation for a satisfying degree program and productive future. Contrarily, poor relationships can frustrate both students and supervisors.
Markey, Mia K.   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

The Development of Interventional Cardiology

open access: yesJournal of the American College of Cardiology, 1998
Twenty years have passed since the beginning of clinical interventional cardiology on the occasion of the first angioplasty procedure performed by Andreas Gruentzig. This discipline, which started as an added technique for physicians who performed cardiac catheterization, has evolved into a ...
openaire   +2 more sources

An Economic Assessment of the Myanmar Rice Sector: Current Developments and Prospects [PDF]

open access: yes, 1998
In this study, the Myanmar rice economy is described in the context of the current political situation and state of national economic development. The forces that are changing rice production and exports are identified; however, the rate of development ...
Cramer, Gail L.   +2 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

An Analysis of Rx for Discovery Reading for Elementary Students Below Grade Level in Reading [PDF]

open access: yes, 2009
Rx for Discovery Reading® is an intervention developed by the National Institute for Learning Development to impact the reading abilities of students below grade level in reading.
Stanley, Susan Kay
core   +1 more source

Achieving the Millennium Development Goal of reducing maternal mortality in rural Africa: an experience from Burundi. [PDF]

open access: yes, 2012
OBJECTIVES: To estimate the reduction in maternal mortality associated with the emergency obstetric care provided by Médecins Sans Frontières (MSF) and to compare this to the fifth Millennium Development Goal of reducing maternal mortality.
Baskett   +19 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Co‐designing a theory‐informed, multicomponent intervention to increase vaccine uptake with Congolese migrants: A qualitative, community‐based participatory research study (LISOLO MALAMU)

open access: yesHealth Expectations
Introduction Disparities in the uptake of routine and COVID‐19 vaccinations have been observed in migrant populations, and attributed to issues of mistrust, access and low vaccine confidence.
Alison F. Crawshaw   +10 more
doaj   +1 more source

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