Results 231 to 240 of about 467,021 (314)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Abu Dhabi Intervention Practice (ADIP)-Agar: A Low-Cost Agar-Based Phantom for Ultrasound-Guided Intervention Training

Indian Journal of Radiology and Imaging
Vijay Ram K. Papineni, Shayeri R. Chowdhury, Rajesh Botchu, Gaurav K. Sharma, Mohamad M. Assker, Amol More   +5 more
doaj   +1 more source

Endoscopic Intermuscular Dissection - Short-term Outcomes. [PDF]

Endosc Int Open
Birzle L, Ebigbo A, Nagl S, Probst A, Ayoub M, Kleinlein I, Messmann H.   +6 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Regional intra-arterial infusion chemotherapy combined with deep hyperthermia and targeted therapy followed by radiotherapy for recurrence with intestinal obstruction after radical resection of rectal cancer in an elderly patient: a case report of individualized treatment. [PDF]

Front Oncol
Zhao G, Yin S, Zhou X, Xu F, Xu L, Wang Q, Zhou J, Zhang L, Liu S.   +8 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Functions of the Index Finger in Musculoskeletal Intervention: A Technical Note

Indian Journal of Radiology and Imaging
Michael Hopkinson, Hasaam Uldin, Kapil Shirodkar, Rajesh Botchu   +3 more
doaj   +1 more source

Interventional treatment for littoral cell angioma of spleen-induced thrombocytopenia: a case report and literature review. [PDF]

Front Oncol
Wu Z, Chen K, Liu Z.
europepmc   +1 more source