Results 51 to 60 of about 390,042 (268)

Modulating CT Attenuation of Polyvinyl Alcohol Cryogels for Individualized Training Phantoms in Interventional Radiology: A Proof-of-Concept Study

open access: yesGels
Anthropomorphic CT phantoms are essential training tools for interventional radiology. Given the high technical demands and stringent safety requirements in this field, realistic CT phantoms are vital simulation tools that support effective hands-on ...
Martin Volk   +7 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Intervention or collaboration? [PDF]

open access: yes, 2020
How can we design and build digital technologies to support people in poor and low-resource environments to achieve their objectives? And how can we do this inclusivelyand ethically, while considering the complexity of their living and working environ-ments?
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Intervention as Intoxication!

open access: yesPerformance Philosophy, 2020
This guest edited journal issue follows on from the Performance Philosophy Biennial 2019 in Amsterdam. Featuring a wide range of research and contribution styles, reworked and elaborated further for this issue, contributors consider alternative ways of ‘intervening’.
Franzen, R., van Balen, S.
openaire   +5 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Comparison of sensory-motor block dynamics after an ultrasound-guided single-point subfascial injection, supraclavicular versus costoclavicular brachial plexus block - A randomised clinical trial

open access: yesIndian Journal of Anaesthesia
Background and Aims: There is limited comparative data on sensory-motor block dynamics following single-point drug delivery between ultrasound guided supraclavicular brachial plexus block and costoclavicular brachial plexus block.
T Sivashanmugam   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Retrospective Analysis of Complications in Central Venous Catheter Insertions: A Single Centre Experience in India

open access: yesIndian Journal of Vascular and Endovascular Surgery
Objectives: This study aimed to analyze the incidence, types, and risk factors associated with central venous catheter (CVC) insertion complications in a tertiary care center in India.
Siddharth Goyal, Vikas Chawla
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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