Results 181 to 190 of about 3,137,787 (316)

UGDH Lactylation Aggravates Osteoarthritis by Suppressing Glycosaminoglycan Synthesis and Orchestrating Nucleocytoplasmic Transport to Activate MAPK Signaling

open access: yesAdvanced Science, EarlyView.
Lactylation of UDP‐glucose dehydrogenase (UGDH) represses its enzymatic activity and causes glycosaminoglycans loss. In addition, UGDH lactylation facilitates its interaction with chromosome region maintenance 1 (CRM1) and promotes the nucleocytoplasmic transport.
Weiren Lan   +8 more
wiley   +1 more source

Interventional Procedures in Superficial Lesions: The Value of 2D with Additional Coronal Reformatted 4D Ultrasonography Guidance [PDF]

open access: green, 2006
Cheng‐Yen Chang   +5 more
openalex   +1 more source

LIPUS Promotes Calcium Oscillation and Enhances Calcium Dependent Autophagy of Chondrocytes to Alleviate Osteoarthritis

open access: yesAdvanced Science, EarlyView.
A non‐invasive and safe physical therapy, low‐intensity pulsed ultrasound (LIPUS) can alleviate osteoarthritis. This study dynamically “visualizes” the invisible mechanical stimuli of LIPUS on living chondrocytes by fluorescence imaging technology in the form of calcium oscillations, confirming LIPUS maintains cartilage homeostasis by promoting ...
Mengtong Guan   +12 more
wiley   +1 more source

1326: Clinical Value of Contrast Enhanced Ultrasonography in Evaluating Interventional Therapeutic Response of Hepatocellular Carcinoma [PDF]

open access: bronze, 2009
Qin Si   +6 more
openalex   +1 more source

Topology‐Optimized Bound States in the Continuum with High‐Q Acoustic Field Enhancement

open access: yesAdvanced Science, EarlyView.
This study presents a topology optimization method for acoustic metamaterials, achieving high‐Q resonances by redesigning a single unit cell within a periodic array. The design enables precise pressure confinement and energy trapping, validated through experiments.
Weibai Li   +2 more
wiley   +1 more source

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

open access: yesAdvanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen   +15 more
wiley   +1 more source

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