A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Musculoskeletal Ultrasound: From Diagnosis to Rehabilitation. [PDF]
Palamar D.
europepmc +1 more source
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo +13 more
wiley +1 more source
Endoscopic ultrasound-guided coil and Histoacryl therapy of varices at the hepaticojejunostomy. [PDF]
Heiduk TR +6 more
europepmc +1 more source
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
A Case Report of Deep Gluteal Syndrome Secondary to Piriformis Enthesopathy Successfully Treated With Ultrasound-Guided Dextrose Prolotherapy. [PDF]
Yoon Y, Sung D, Lee J, Lam KHS.
europepmc +1 more source
Anatomic and hemodynamic characterization of vertebral artery duplication via color doppler ultrasonography. [PDF]
Han X +6 more
europepmc +1 more source
Positive association of lipoprotein(a) and the prevalence of lower extremity arterial disease in MASLD: a cross-sectional study. [PDF]
Wu Z +8 more
europepmc +1 more source
Chronic Enlarged Iatrogenic Radial Arteriovenous Fistula. [PDF]
Takeyama M +5 more
europepmc +1 more source

