Results 91 to 100 of about 4,020,664 (302)

“I Don’t Have Time to Exercise”: Determinants of Physical Activity and Diet Consumption Among Adolescents Living with HIV in Southern Tanzania – A Phenomenological Qualitative Study

HIV/AIDS: Research and Palliative Care
Justina J Maganga,1,2 Andrew Katende,1,3 Ezekiel Luoga,3 Nancy Nshatsi,2,4 Jamal Siru,1,3 George Sigalla,1,3 Clara Mollay,2 Maja Weisser,1,3,5,6 Sally Mtenga7 1Interventions and Clinical Trials, Ifakara Health Institute, Morogoro, Tanzania; 2The Nelson ...
Maganga JJ, Katende A, Luoga E, Nshatsi N, Siru J, Sigalla G, Mollay C, Weisser M, Mtenga S   +8 more
doaj  

How to design and evaluate interventions to improve outcomes for patients with multimorbidity [PDF]

, 2013
Multimorbidity is a major challenge for patients and healthcare providers. The limited evidence of the effectiveness of interventions for people with multimorbidity means that there is a need for much more research and trials of potential interventions ...
Stewart W. Mercer, Fortin, M, Martin Fortin, Vestergaard, M., Sally Wyke (3408131), Elizabeth A. Bayliss, Vestergaard, Mogens, Bayliss, Elizabeth A., Wyke, S, Gunn, J, Mercer, S.W., Mercer, Stewart W., Smith, SM, Bayliss, EA, Susan M. Smith, Salisbury, C., Sally Wyke, Martin Fortin (3405860), Smith, S.M., Wyke, S., Elizabeth Bayliss (3466778), Salisbury, Chris, Susan Smith (7896224), Gunn, Jane, Chris Salisbury, Gunn, J., Jane Gunn, Jane Gunn (21050), Bayliss, E.A., Fortin, M., Mogens Vestergaard, Salisbury, C, Mercer, SW, Moogens Vestergaard (7945238), Stewart Mercer (811562), Wyke, Sally, Vestergaard, M, Fortin, Martin, Smith, Susan M., Chris Salisbury (601799)   +39 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Equity-focused analysis of tailoring strategies for overcoming risk factors in ethnic minorities (EQUATOR): a protocol for a scoping review with a realist analysis

BMJ Open
Introduction Chronic diseases driven by modifiable risk factors (MRFs), such as poor diet, physical inactivity, tobacco use and harmful alcohol consumption, disproportionately affect ethnic minority groups worldwide and within multi‑ethnic societies such
Nick Sevdalis, G.J. Melendez-Torres, Jumana Hashim, Conor Luck, Niharika Rustagi   +4 more
doaj   +1 more source

Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

Journal of Translational Medicine, 2019
Background Magnetic resonance guided focused ultrasound was suggested for the induction of deep localized hyperthermia adjuvant to radiation- or chemotherapy.
Pauline C. Guillemin, Laura Gui, Orane Lorton, Thomas Zilli, Lindsey A. Crowe, Stéphane Desgranges, Xavier Montet, Sylvain Terraz, Raymond Miralbell, Rares Salomir, Sana Boudabbous   +10 more
doaj   +1 more source

Should brief interventions in primary care address alcohol problems more strongly? [PDF]

, 2013
BACKGROUND: Brief interventions have well-established small effects on alcohol consumption among hazardous and harmful drinkers in primary care, and national large-scale programmes are being implemented in many countries for public health reasons ...
McCambridge, Jim, Rollnick, Stephen
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

TEHIP news, issue no. 5 : community participation; health information package; malaria strategic planning

, 2002
"A newsletter of the IDRC/MOH Tanzania Essential Health Interventions Project"With support from the Council Health Management Teams, communities in both Rufiji and Morogoro Rural districts (Tanzania) have mobilized resources to rehabilitate health ...
Tanzania Essential Health Interventions Project
core   +1 more source

Optimising the acceptability and feasibility of novel complex interventions: an iterative, person-based approach to developing the UK Morita therapy outpatient protocol

Pilot and Feasibility Studies, 2017
Background The aim of this paper is to showcase best practice in intervention development by illustrating a systematic, iterative, person-based approach to optimising intervention acceptability and feasibility, as applied to the cross-cultural adaptation
Holly Victoria Rose Sugg, David A. Richards, Julia Frost   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source