Results 121 to 130 of about 50,057 (320)

Juvenile polyposis in a SMAD4‐mutated child: A call for early surveillance

open access: yesJPGN Reports, EarlyView.
Abstract We report the case of a 10‐year‐old boy with hereditary hemorrhagic telangiectasia (HHT) and a family history of SMAD4‐related juvenile polyposis syndrome (JPS), presenting with hypoferritinaemia unresponsive to oral supplementation. Endoscopic evaluation revealed multiple gastrointestinal polyps, including duodenal, gastric, and colonic ...
Claudia Lorusso   +10 more
wiley   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Correlation between sigmoid interventricular septum angle and presence of Q waves on the electrocardiogram

open access: diamond, 2022
Athanasios Kartalis   +10 more
openalex   +2 more sources

Repeatability of Rapid Human Cardiac Phosphorus MRSI (31P‐MRSI) Using Concentric Ring Trajectory Readouts at 7 T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose PCr/ATP ratio is determined at 7 T typically using Fourier‐transform based magnetic resonance spectroscopic imaging sequences (FT‐MRSI). These sequences require acquisition times longer than desirable for inclusion in cardiac clinical trials. Concentric ring trajectory (CRT‐MRSI) has been described as an accelerated alternative k‐space
Ferenc E. Mózes   +8 more
wiley   +1 more source

Cardiac resynchronization therapy and pulmonary artery banding in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block

open access: yesPediatric Investigation, EarlyView.
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng   +8 more
wiley   +1 more source

Cardiac dysfunction during adverse maternal outcomes in hypertensive disorders of pregnancy

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In pregnancies complicated by hypertensive disorders, peripartum adverse maternal outcomes are associated with diastolic cardiac dysfunction. Elevated E/e' ratio and left atrial volume index highlight the need for targeted cardiovascular monitoring and long‐term follow‐up.
Veronica Giorgione   +5 more
wiley   +1 more source

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero   +11 more
wiley   +1 more source

GENDER SPECIFICS OF HEART REMODELLING AND CIRCADIAN BLOOD PRESSURE PROFILE IN PATIENTS WITH ARTERIAL HYPERTENSION

open access: yesРоссийский кардиологический журнал, 2009
The examination of 126 patients with Stage II arterial hypertension (AH) demonstrated that in men, progressing left ventricular hypertrophy (LVH) was associated with increased free wall thickness and especially interventricular septum thickness, without ...
K. A. Abramova, V. V. Mazur, E. S. Mazur
doaj  

Transcriptional and functional effects of mavacamten in multiple porcine and human models with hypertrophic cardiomyopathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Mavacamten (MAVA) is a novel small molecule inhibitor of cardiac myosin, mitigating cardiomyocyte hypercontractility in patients with hypertrophic obstructive cardiomyopathy (HOCM). Despite its recent approval for clinical use, the transcriptional and functional impacts of MAVA remain not well understood.
Elisa Kiselev   +36 more
wiley   +1 more source

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