Results 141 to 150 of about 113,031 (301)

Difference in pre‐ and postnatal prevalence of congenital cardiac tumors in a large population‐based cohort

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Ultrasonic assessment of a large, contemporary cohort in Copenhagen, Denmark, revealed a prevalence of congenital cardiac tumors of 0.002% prenatally (gestational Weeks 18–21) and 0.027% postnatally. All cardiac tumors were located in the ventricles.
Anne‐Sophie Sillesen   +9 more
wiley   +1 more source

Dissecting aneurysms of the interventricular septum [PDF]

open access: bronze, 2003
Shiv Kumar Choudhary   +2 more
openalex   +1 more source

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou   +16 more
wiley   +1 more source

Super‐Enhancer Target Gene CBP/p300‐Interacting Transactivator With Glu/Asp‐Rich C‐Terminal Domain, 2 Cooperates With Transcription Factor Forkhead Box J3 to Inhibit Pulmonary Vascular Remodeling

open access: yesCell Proliferation, EarlyView.
During hypoxia, the transcriptional effect of super‐enhancer in promoting CBP/p300‐interacting transactivator with Glu/Asp‐rich C‐terminal domain, 2 reduced, eventually leading to the thickening of the smooth muscle layer of the pulmonary artery.
Songyue Li   +11 more
wiley   +1 more source

Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy. [PDF]

open access: yesCirc Genom Precis Med, 2023
Yu M   +13 more
europepmc   +1 more source

Right ventricular functional recovery after acute myocardial infarction: relation with left ventricular function and interventricular septum motion. GISSI-3 echo substudy [PDF]

open access: bronze, 2005
Bogdan A. Popescu   +13 more
openalex   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

open access: yesThe FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés   +19 more
wiley   +1 more source

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

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