Results 171 to 180 of about 50,057 (320)

A Case of Atrial Septal Defect Unveiled by the Treatment for Pulmonary Arterial Hypertension

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT We present a case of a 51‐year‐old woman with atrial septal defect (ASD) masked by pulmonary arterial hypertension (PAH). Three months after PAH treatment with a combination of endothelin receptor antagonist and phosphodiesterase five inhibitor, the transthoracic echocardiography revealed left‐to‐right shunting through a secundum ASD.
Takaaki Fujii   +12 more
wiley   +1 more source

Apical Sparing of Longitudinal Strain and Myocardial Fibrosis in Hypertensive Patients and Spontaneously Hypertensive Rats: Based on Speckle Tracking and Histological Analysis

open access: yesClinical Cardiology, Volume 49, Issue 1, January 2026.
Hypertensive cardiac hypertrophy shows a “basal‐damage, apical‐sparing” pattern in strain and fibrosis. This apical sparing correlates with diastolic dysfunction and hypertrophy progression, highlighting its value as an observable clinical hallmark of adverse remodeling. ABSTRACT Background This study aimed to investigate regional myocardial strain and
Chunyan Huang   +6 more
wiley   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao   +7 more
wiley   +1 more source

Ultrasound‐Based Z Score and Pulmonary Valve/Aortic Valve Diameter Ratio Improving the Predictive Value of Fetal Aortic Stenosis

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 1, Page 64-72, January 2026.
A total of 24 singleton fetuses with suspected AS who underwent two or more fetal echocardiograms were enrolled in this study. Using electronic spatiotemporal image correlation (eSTIC) technology, the AV and PV Z scores, along with the PV/AV ratio, were measured and compared between two echocardiographic examinations to assess diagnostic efficacy ...
M. Heqing Guo   +4 more
wiley   +1 more source

Genetic Determinants of the Interventricular Septum Are Linked to Ventricular Septal Defects and Hypertrophic Cardiomyopathy. [PDF]

open access: yesCirc Genom Precis Med, 2023
Yu M   +13 more
europepmc   +1 more source

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