Results 231 to 240 of about 68,127 (346)

Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review. [PDF]

Front Surg
Wang Y, Zhao X, Zhang X, Yang Y, Zhang W, Liu S, Liu Z, Zhang L, Wang K, Wu H.   +9 more
europepmc   +1 more source

Canonical Wnt signaling in the notochordal cell is upregulated in early intervertebral disk degeneration [PDF]

, 2011
Lucas A. Smolders, Björn P. Meij, Frank M. Riemers, Ruud Licht, Richard Wubbolts, Douwe van den Heuvel, Guy C. M. Grinwis, J.C.M. Vernooij, Herman A.W. Hazewinkel, Louis C. Penning, Marianna A. Tryfonidou   +10 more
openalex   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Morphology of the Cartilaginous Endplates in Human Intervertebral Disks with Ultrashort Echo Time MR Imaging [PDF]

, 2012
Won C. Bae, Sheronda Statum, Zhao Zhang, Tomonori Yamaguchi, Tanya Wolfson, Anthony Gamst, Jiang Du, Graeme M. Bydder, Koichi Masuda, Christine B. Chung   +9 more
openalex   +1 more source

Optimisation of Intervertebral Disc Mechanical Properties and the Impact of Vertebral Alignment in Subject‐Specific Finite Element Models

International Journal for Numerical Methods in Biomedical Engineering, Volume 41, Issue 6, June 2025.
Optimisation methods were compared for a porcine lumbar intervertebral disc model. Neither optimising with 6‐axis forces and moments nor optimising with disc pressures fully captured spinal behaviour. Addressing model limitations could improve the process.
Emily S. Kelly, Akbar A. Javadi, Timothy P. Holsgrove, Michael Ward, David Williams, Jenny Williams, Cathy Holt, Judith R. Meakin   +7 more
wiley   +1 more source

The Role of Microvascular Variations in the Process of Intervertebral Disk Degeneration and Its Regulatory Mechanisms: A Literature Review. [PDF]

Orthop Surg
Zhang SP, Tong M, Li SD, Zhang B, Zhang W, Wang R, Dong ZY, Huang YF.   +7 more
europepmc   +1 more source

Effect of acupuncture on the energy metabolism of dogs with intervertebral disk disease and cervical disk herniation: A pilot study. [PDF]

Vet Res Commun, 2023
Sawamura M, Arai T, Kawasumi K.
europepmc   +1 more source

Accuracy, intermethod agreement, and inter-reviewer agreement for use of magnetic resonance imaging and myelography in small-breed dogs with naturally occurring first-time intervertebral disk extrusion [PDF]

, 2012
Alexandra Squires Bos, Brigitte A. Brisson, Stephanie Nykamp, Roberto Poma, Robert A. Foster   +4 more
openalex   +1 more source

Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique

JOR SPINE, Volume 8, Issue 2, June 2025.
The current study improves cyber toxicology as a method of evaluating environmental toxicity and molecular biological qualities in addition to clarifying the possible molecular pathways of nicotine‐induced senescence in IVDD. ABSTRACT Aim Through the use of network toxicology, the research sought to determine whether cellular senescence and associated ...
Chen Jiang, Chao Song, Chaoqi Chen, Baoxin Shen, Lei Yang, Chi Zhang, Fei Liu, Xiaofei Wu, Feng Chen   +8 more
wiley   +1 more source

The role of micronutrients and serum metabolites in intervertebral disk degeneration: insights from a Mendelian randomization study and mediation analysis. [PDF]

Front Nutr
Jiang N, Wang Q, Jiang J, Li L.
europepmc   +1 more source