Results 261 to 270 of about 68,127 (346)

Molecular Subtypes and Immune Microenvironment Characterization of the Annulus Fibrosus in Intervertebral Disc Degeneration: Insights From Translation Factor‐Related Gene Analysis

JOR SPINE, Volume 8, Issue 2, June 2025.
TFGs are valuable for distinguishing between different IVDD clusters. The predictive model developed demonstrates strong performance in forecasting IVDD. A thorough analysis of these clusters can contribute to a deeper understanding of the molecular mechanisms of IVDD.
Sikuan Zheng, Xiaokun Zhao, Hui Wu, Xuhui Cuan, Xigao Cheng, Dingwen He   +5 more
wiley   +1 more source

Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy. [PDF]

JOR Spine
Xu T, Zhao H, Li J, Fang X, Wu H, Hu W.
europepmc   +1 more source

1302 A Study on Non-invasive Estimation Method of the Load to Hang at Intervertebral Disk

, 2009
Shinji Yamamoto, Yoshio INOUE, Kyoko SHIBATA   +2 more
openalex   +2 more sources

Gene Expression Profiling of Early Intervertebral Disk Degeneration [PDF]

, 2012
L. Smolders, B. Meij, D. Onis, F. Riemers, N. Bergknut, R. Wubbolts, G. Grinwins, Marian J.A. Groot Koerkamp, F. Holstege, H. Hazewinkel, L. Creemers, Lisa M. Penning, Marianna A. Tryfonidou   +12 more
openalex   +1 more source

Mechanisms and Therapeutic Strategies of Macrophage Polarization in Intervertebral Disc Degeneration

JOR SPINE, Volume 8, Issue 2, June 2025.
This article reviews the role of macrophage polarization in IVDD. It details how macrophage polarization influences various pathomechanisms of disc degeneration, including the inflammatory microenvironment, NPCs senescence, angiogenesis, fibrosis, and neural ingrowth and sensitization.
Kaiyuan Zheng, Siyu Wang, Meng Deng, Yaomin Luo, Wen Li, Lianlin Zeng, Yinxu Wang   +6 more
wiley   +1 more source

An In Situ Anti-Inflammatory Drug Delivery System for Intervertebral Disks [PDF]

, 2012
Inês Pereira, Mariana Barbosa, Raquel M. Gonçalves, Clodomir de Jesus Costa Pereira, M. Molinos   +4 more
openalex   +1 more source

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

JOR SPINE, Volume 8, Issue 2, June 2025.
Within this manuscript, bioinformatics and experimental methods are used to explore the role of circadian rhythm and immunity in Intervertebral Disc Degeneration (IVDD). CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI were successfully demonstrated to be hub rhythm‐related genes in the process of IVDD together with immunity.
Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang   +5 more
wiley   +1 more source

Causal effects of skin microbiota on intervertebral disk degeneration, low back pain and sciatica: a two-sample Mendelian randomization study. [PDF]

J Orthop Surg Res
Jia Y, Chen H, Huang S, Huo Z, Xu B.
europepmc   +1 more source

Novel Molecular Phenotype of Notochordal-Like Cells in Nucleus Pulposus of Human Intervertebral Disk [PDF]

, 2012
X. Tang, L. Jing, L. Setton, W. Richardson, R. Fitch, R. Isaacs, C. Brown, J. Chen   +7 more
openalex   +1 more source

Dorsal laminectomy for treatment of cervical vertebral stenotic myelopathy in an alpaca [PDF]

Barker, W H J, Driver, C J, Jull, P, Volk, H A, Whitehead, C E, Witte, T H   +5 more
core   +1 more source