Results 51 to 60 of about 34,930 (276)

Dynamic Lumbosacral Magnetic Resonance Imaging in a Dog with Tethered Cord Syndrome with a Tight Filum Terminale [PDF]

, 2017
A 1-year and 11-month- old English Cocker Spaniel was evaluated for clinical signs of progressive right pelvic limb lameness and urinary incontinence. Neurological examination was suggestive of a lesion localized to the L4–S3 spinal cord segments.
De Decker, De Lahunta, De Vloo, Filipiddis, Fletcher, Hendson, Hertzler, Johnson, Lew, Michelson, Nakanishi, Ostling, Rade, Rade, Rade, Saker, Tu, Yamada, Yamada   +18 more
core   +2 more sources

LINC00969 promotes the degeneration of intervertebral disk by sponging miR‐335‐3p and regulating NLRP3 inflammasome activation

IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2019
Long noncoding RNAs (LncRNAs) may serve as miRNA sponges to regulate the expressions of miRNA target genes. LncRNA LINC00969 has been indicated to be upregulated in intervertebral disk degeneration.
Lei Yu, Yingjie Hao, chaojun Xu, Guangduo Zhu, Yingchun Cai   +4 more
semanticscholar   +1 more source

Tissue Engineering for Intervertebral Disk Degeneration [PDF]

, 2011
Many challenges confront intervertebral disk engineering owing to complexity and the presence of extraordinary stresses. Rebuilding a disk of native function could be useful for removal of the symptoms and correction of altered spine kinematics ...
Chan, BP, Chan, D, Cheung, KMC, Leung, VYL, Tam, V   +4 more
core   +1 more source

Sericin/crocetin micro/nanoparticles for nucleus pulposus cells regeneration: An “active” drug delivery system

Frontiers in Pharmacology, 2023
Introduction: Initiation and progression of intervertebral disk degeneration are linked to oxidative stress, with reactive oxygen species being a key factor.
Elia Bari, Sara Perteghella, Giovanna Rassu, Elisabetta Gavini, Giacomo Luigi Petretto, Maria Cristina Bonferoni, Paolo Giunchedi, Maria Luisa Torre   +7 more
doaj   +1 more source

Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration

Frontiers in Pharmacology, 2019
Intervertebral disk degeneration (IDD) is the major cause of low back pain (LBP), which affects 80% of the world’s population. Interleukin 1 beta (IL-1β) is a major inflammatory factor that accelerates disk degeneration, and IL-1β levels increase in ...
Jialiang Lin, Jiaoxiang Chen, Zengjie Zhang, Tianzhen Xu, Zhenxuan Shao, Xiaobin Wang, Yuanzhe Ding, Naifeng Tian, Haiming Jin, Sunren Sheng, Weiyang Gao, Yan Lin, Xiaolei Zhang, Xiangyang Wang   +13 more
semanticscholar   +1 more source

Case report: Double adjacent ventral slot in two medium-sized breed dogs

Frontiers in Veterinary Science
Two medium-sized, 7-year-old dogs, with no previous history of pain, presented with acute neurologic symptoms consistent with intervertebral disk disease. Both cases had CT, where cervical pathology was identified.
Razvan Grigore Cojocaru, Bogdan Sicoe, Cristina Gaspar, Alexandra Grigoreanu, Gabriel Orghici, Ioan Tibru, Radu Lacatus   +6 more
doaj   +1 more source

Obesity Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances via MAPK Pathway Activation in Intervertebral Disk Degeneration

Frontiers in Physiology, 2019
Obesity may promote intervertebral disc degeneration (IDD) by non-mechanical means, by influencing levels of free fatty acids which could impair cell metabolism.
Xuyang Zhang, Jian Chen, Bao Huang, Jiasheng Wang, Z. Shan, Jun-hui Liu, Yi-lei Chen, Shengyun Li, S. Fan, F. Zhao   +9 more
semanticscholar   +1 more source

Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs [PDF]

, 2018
Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and ...
BA Brisson, CW Dewey, DR Westworth, E Schlensker, E Schlensker, F Wang, Gert ter Haar, GI Hristova, HG Parker, HK Chang, Holger A. Volk, IA Stokes, J Guevar, J Street, K Faller, LA Smolders, LM De Rycke, M Charalambous, MA Stone, Maria Claudia C. M. Inglez de Souza, MP Abdel, MS Mogensen, MS Mogensen, MS Yau, N Bergknut, ND Jeffery, O Epstein, P Bernstein, P Moissonnier, R Gutierrez-Quintana, RC Brink, Richard Ryan, RM Packer, Rowena M. A. Packer, S De Decker, SA Gomes, SD Decker, Steven De Decker, T Aikawa, T Aikawa   +39 more
core   +3 more sources

CT-Scan Based Evaluation of Dorsal-to-Ventral Ratios of Paraspinal Musculature in Chondrodystrophic and Non-chondrodystrophic Dogs

Frontiers in Veterinary Science, 2020
Objective: To assess and objectively quantify, with CT-scan exams, differences in cervical paraspinal musculature and vertebrae angulation that might influence the different predisposed sites for intervertebral disk disease observed in chondrodystrophic ...
Katinka Hartmann, Pia Düver, Stephan Kaiser, Carolin Fischer, Franck Forterre   +4 more
doaj   +1 more source

Results at 24 months from the prospective, randomized, multicenter Investigational Device Exemption trial of ProDisc-C versus anterior cervical discectomy and fusion with 4-year follow-up and continued access patients. [PDF]

, 2010
BackgroundCervical total disk replacement (TDR) is intended to address pain and preserve motion between vertebral bodies in patients with symptomatic cervical disk disease.
Darden, Bruce, Delamarter, Rick B, Goldstein, Jeffrey A, Janssen, Michael E, Murrey, Daniel, Tay, Bobby K-B, Zigler, Jack   +6 more
core   +1 more source