Results 251 to 260 of about 3,098,056 (351)

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

open access: yesAdvanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou   +5 more
wiley   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

open access: yesAdvanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett   +13 more
wiley   +1 more source

FACILITY: feeding the family-the intergenerational approach to fight obesity, a cross-sectional study protocol. [PDF]

open access: yesFront Pediatr
Vincenti A   +9 more
europepmc   +1 more source

An In Situ Curing, Shear‐Responsive Biomaterial Designed for Durable Embolization of Microvasculature

open access: yesAdvanced Healthcare Materials, EarlyView.
NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham   +16 more
wiley   +1 more source

Short‐Chain Fatty Acids Modulate Anti‐ROR1 CAR T‐Cell Function and Exhaustion in an Intestinal Adenocarcinoma‐on‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Short‐chain fatty acids modulate anti‐ROR1 chimeric antigen receptor (CAR) T‐cell function in an intestinal adenocarcinoma‐on‐chip model. Butyrate and propionate reduce cytotoxicity, cytokine release, and infiltration by inducing a regulatory T‐cell phenotype and T‐cell exhaustion via histone deacetylase inhibition.
Valentin D. Wegner   +5 more
wiley   +1 more source

The smart senior care demand in China in the context of active ageing: a qualitative study with multiple perspectives. [PDF]

open access: yesFront Public Health
Huang Q   +10 more
europepmc   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

open access: yesAdvanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu   +9 more
wiley   +1 more source

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