Results 281 to 290 of about 6,290,967 (378)

Inductive‐Associative Meta‐learning Pipeline with Human Cognitive Patterns for Unseen Drug‐Target Interaction Prediction

open access: yesAdvanced Science, EarlyView.
Predicting unseen drug‐target interactions is challenging. BioBridge presents an Inductive‐Associative pipeline inspired by scientists' workflow. It combines transferable binding principles, learned via multi‐level encoders and adversarial training, with insights from weakly related references through meta‐learning.
Xiaoqing Lian   +11 more
wiley   +1 more source

Identification and synthesis of end-of-life decision-making measures: a scoping review. [PDF]

open access: yesFront Med (Lausanne)
Bucko P   +13 more
europepmc   +1 more source

Interview

open access: yesPathogens and Global Health, 2012
openaire   +2 more sources

Modulating Macrophage–Nucleus Pulposus Cell Crosstalk via Sequential Drug Delivery Attenuates Disc Degeneration

open access: yesAdvanced Science, EarlyView.
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong   +12 more
wiley   +1 more source

A Lipid with Lewis Pair‐Mediated Targeting and Multiple Stimuli‐Responsive Delivery of Antibiotics for Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Lewis pair‐integrated lipids (Lp‐lipids), combining targeted delivery and stimuli‐responsive are developed for antibiotic delivery. These lipids form nanoparticles that bind biofilms via boronate ester bonds and respond to acidic pH, H2O2, and ATP, enabling controlled drug release.
Xiaojian Yan   +11 more
wiley   +1 more source

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