Results 31 to 40 of about 740,536 (217)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

PROF. HILARY COOPER İLE KÜÇÜK ÇOCUKLARLA TARİH ÖĞRETİMİ ÜZERİNE BİR GÖRÜŞME

open access: yesTurkish History Education Journal, 2019
Prof. Hilary Cooper ile küçük çocuklarla tarih öğretimi üzerine bir görüşme.
Yasin DOĞAN
doaj   +1 more source

Paul Auster. Gli Stati Uniti, la politica, la scrittura

open access: yesIperstoria, 2020
Questa intervista si è svolta alla fine di luglio 2019 nella abitazione di Paul Auster a Brooklyn, New York. Un estratto del testo è andato in onda all’interno della trasmissione TV7 di RAI 1 (29 novembre 2019).
Oliviero Bergamini
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Bulhaři a další Balkánci v Česku. Metodologické, pedagogické a heuristické aspekty studentských výzkumů [PDF]

open access: yesStudia Ethnologica Pragensia, 2016
To acquire how to do an ethnographic field research of the living society and culture is a part of the university ethnology studies. The author deals with several examples of student’s field researches in the Czech Republic, Slovakia and Bulgaria in the ...
Helena Bočková
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Teleradiology of Korea in 2017: Survey and Interview of Training Hospitals and Teleradiology Center

open access: yes대한영상의학회지, 2019
Purpose Teleradiology has been widely used nationwide in various ways. In order to prepare a guideline, it was recognized that a survey on the actual condition of teleradiology in Korea was necessary.
Hyunsik Woo   +10 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The policy-practice gap: supporting national VISION 2020 action plans

open access: yesCommunity Eye Health Journal, 2004
Dr Etya'ale, can you tell us what your work involves? My job is to help countries in Africa develop and implement their national VISION 2020 action plans.
An interview with Daniel Etya’ale
doaj  

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