Results 61 to 70 of about 4,028,912 (286)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
A Window Into the Bright Side of Psychology: Interview With Mihaly Csikszentmihalyi
Europe's Journal of Psychology, 2017 Mihaly Csikszentmihalyi is one of the most eminent psychologists of the modern era. His ideas, such as flow, or the systems model of creativity, have inspired numerous studies, theoretical analyses as well as pedagogic and psychological interventions ...
Mihaly Csikszentmihalyi, Izabela Lebuda
doaj +1 more source
, 2009 The respondent tells of her experiences of decollectivization.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu ...
G.yu lha
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Interview with Kathryn Peek [PDF]
, 2017 An oral history interview with Kathryn Elaine Hickman Peek about her career as a biomedical administrator and educator at many institutions in the Texas Medical Center. Kathryn Elaine Peek, Ph.D. completed her bachelor’s degree in English and embarked on
Peek, Kathryn Elaine, Ph.D.
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Interview with Melinda Perrin [PDF]
, 2017 An oral history interview with Melinda Perrin about her career in the Texas Medical Center and work on the board of Hermann Hospital and later Memorial Hermann Healthcare System.
Perrin, Melinda H.
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Cristian Diaconescu: „Campania din Afganistan a fost un pas decisiv pentru integrarea noastră în Alianța Nord-Atlantică” [PDF]
Polis: Revista de Stiinte Politice, 2022 Interview with Cristian ...
Sorin BOCANCEA
doaj
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source