Results 71 to 80 of about 3,098,056 (351)
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Focus-group interview and data analysis
Proceedings of the Nutrition Society, 2004 In recent years focus-group interviews, as a means of qualitative data collection, have gained popularity amongst professionals within the health and social care arena.
F. Rabiee
semanticscholar +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Florian Bichir: „Trianon, 4 iunie 1920 – Transilvania s-a întors pentru totdeauna acasă” [PDF]
Polis: Revista de Stiinte Politice, 2020 Interview with Florian ...
Ioana Drăgulin
doaj
Schizophrenia bulletin, 2003 As the number of studies related to the early identification of and intervention in the schizophrenia prodrome continues to grow, it becomes increasingly critical to develop methods to diagnose this new clinical entity with validity.
T. Miller +9 more
semanticscholar +1 more source
Qualitative Interview Questions: Guidance for Novice Researchers
, 2020 This article, aimed at the novice researcher, is written to address the increased need to develop research protocols or interview guides to meet the requirements set by IRBs and human subjects review committees.
Roberts, E. Rosanne
semanticscholar +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Exploring Emerging Technologies for Requirements Elicitation Interview Training: Empirical Assessment of Robotic and Virtual Tutors [PDF]
arXiv, 2023 Requirements elicitation interviews are a widely adopted technique, where the interview success heavily depends on the interviewer's preparedness and communication skills. Students can enhance these skills through practice interviews. However, organizing practice interviews for many students presents scalability challenges, given the time and effort ...
arxiv
Patient Related Outcome Measures, 2020 Avery A Rizio,1 Lynne E Broderick,1 Michelle K White,1 Tiffany P Quock2 1Optum Life Sciences, Patient Insights, Johnston, RI, USA; 2Prothena Biosciences Inc, South San Francisco, CA, USACorrespondence: Avery A RizioOptum Life Sciences, Patient Insights ...
Rizio AA +3 more
doaj
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source