Results 81 to 90 of about 4,028,912 (286)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

In the PaLRaP Spotlight: Emily Reed, Reference and Instruction Librarian

open access: yesPennsylvania Libraries: Research & Practice
An interview with Emily ...
Denise Wetzel
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Political interview [PDF]

open access: yes
Paraphrasing, reading between the lines and ...
EPDP, Keleta and Mesfin   +1 more
core  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Being a manager, becoming a professional? A case study and interview-based exploration of the use of management knowledge across communities of practice in health-care organisations

open access: yesHealth Services and Delivery Research, 2014
Background: Understanding how managers in the NHS access and use management knowledge to help improve organisational processes and promote better service delivery is of pressing importance in health-care ...
Mike Bresnen   +4 more
doaj   +1 more source

Interview with Meghan Daum [PDF]

open access: yes, 2017
Meghan Daum is the author of four books, most recently the collection of original essays The Unspeakable: And Other Subjects of Discussion, which won the 2015 PEN Center USA Award for creative nonfiction.
Wylie, Julian
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

The potential of alternatives to face-to-face consultation in general practice, and the impact on different patient groups: a mixed-methods case study

open access: yesHealth Services and Delivery Research, 2018
Background: There is international interest in the potential role of different forms of communication technology to provide an alternative to face-to-face consultations in health care.
Helen Atherton   +8 more
doaj   +1 more source

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