Results 31 to 40 of about 4,775,368 (286)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Qualitative Research Interviews [PDF]

open access: yes, 2009
After presenting a brief overview of the complexity of the qualitative interviewing process used by psychotherapy researchers, the authors discuss some of the major ideas that psychotherapy researchers using such interviews must consider both before and ...
Burkard, Alan W., Knox, Sarah
core   +1 more source

An examination of "don't know" responses in forensic interviews with children [PDF]

open access: yes, 2014
Most experimental studies examining the use of pre-interview instructions (ground rules) show that children say “I don't know” more often when they have been encouraged to do so when appropriate.
Bruck   +39 more
core   +4 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Critical Realist Philosophy and the Possibility of an Eco-decolonial Museology

open access: yesMuseum & Society, 2021
New forms of museum practice that explore the dynamics of social and ecological processes as interlinked systems are increasingly urgent. Critical realist philosophy is used to consider the emergence of tensions between museological processes of ...
Thomas Carnegie Jeffery
doaj   +1 more source

Interviews of deshopping behaviour: An analysis of theory of planned behaviour [PDF]

open access: yes, 2003
Research reveals alarming results on the prevalence of the dishonest consumer behaviour known as deshopping. Deshopping is the “deliberate return of goods for reasons other than actual faults in the product, in its pure form premeditated prior to and ...
Dennis, C, King, T
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Participants’ home as an interview context when studying sensitive family issues

open access: yesJournal of Comparative Social Work, 2013
This article considers the meaning of the participants’ home as an interview context when studying sensitive family issues. The article is based on two qualitative family studies by the authors on foster children’s perspectives on their home and their ...
Kati Hämäläinen, Susanna Rautio
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Intoxicated eyewitnesses:the effects of alcohol on eyewitness recall across repeated interviews [PDF]

open access: yes, 2013
The study evaluated the usefulness of repeat-interviewing of witnesses to crimes who were intoxicated by alcohol at the time of the incident and their first interview, and then re-interviewed when not intoxicated the following day.
La Rooy, David J.   +2 more
core   +5 more sources

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