Results 61 to 70 of about 4,900,725 (310)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Breathing through a troubled life – a phenomenological-hermeneutic study of chronic obstructive pulmonary disease patients’ lived experiences during the course of pulmonary rehabilitation

open access: yesInternational Journal of Qualitative Studies on Health & Well-Being, 2019
Purpose: Exploring real-life experiences of Chronic Obstructive Pulmonary Disease (COPD) patients during rehabilitation can contribute with new knowledge of what has significance for their participation and chance for improved health and well-being ...
Charlotte Simonÿ   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Final Evaluation Report: Early Childhood Connections Program (ECCP) Parent Interviews [PDF]

open access: yes, 2012
Presents findings from interviews with guardians referred to developmental or behavioral programs for their children through the ECCP about their use of and satisfaction with services and suggestions for ...

core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Advantages and limitations of virtual online consultations in a NHS acute trust: the VOCAL mixed-methods study

open access: yesHealth Services and Delivery Research, 2018
Background: There is much enthusiasm from clinicians, industry and the government to utilise digital technologies and introduce alternatives to face-to-face consultations. Objective(s): To define good practice and inform digital technology implementation
Sara Shaw   +10 more
doaj   +1 more source

Forensic interviews with children in Scotland: a survey of interview practices among police. [PDF]

open access: yes, 2010
The present study surveyed 91 police interviewers in Scottish police forces about their perceptions of how well they adhered to the Scottish Executive (2003) guidelines.
La Rooy, David J.   +2 more
core   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

How Agritourism Operators Make Marketing and Promotion Decisions

open access: yesJournal of Human Sciences and Extension, 2023
Agritourism operators in Oklahoma were interviewed to determine how they make promotional decisions. Three themes were found from the interviews. The first was Educated Guessing. Participants were not formally trained in promoting agritourism operations,
Katelyn Miller   +3 more
doaj  

Conducting interviews about penile cancer: A patient-conducted-interview study [PDF]

open access: yes, 2010
Objectives: Penile cancer is a rare but destructive condition. It has been found to be detrimental to body image, general health and sexual functioning, while increasing anxiety and social problems.
Branney, P, Eardley, I, Witty, K
core  

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