Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Understanding how post-intensive care follow-up is delivered within the role of critical care outreach teams: a qualitative study protocol. [PDF]
Bonner A +5 more
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
The topicalization of culture in Cambridge undergraduate admissions interviews
Abstract This article explores how candidates discuss cultural topics that overlap with their sociocultural background during the Cambridge undergraduate admissions interviews, an academic gatekeeping encounter. On the one hand, discussion of this kind can be a source of epistemic authority for these candidates.
openaire +1 more source
Interviews topic guides_ENG (version 2).pdf
Map the available sources of datasets about access to and use of medicines among migrant populations.
Meukens, Loes, Aljadeeah, Saleh
openaire +1 more source
Diabetes-related barriers to cancer screening in women with type 2 diabetes: A qualitative interview study. [PDF]
Spencer R +5 more
europepmc +1 more source
Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li +9 more
wiley +1 more source
Mixed-methods analysis on psychedelic-augmented meditation experiences from a randomized controlled mindfulness retreat. [PDF]
Schlomberg JTT +5 more
europepmc +1 more source
MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
Psychological relation of tandem nursing to children's socio-emotional development and attachment to their caregiver. [PDF]
Lund J, Trostmann J, Kulke L.
europepmc +1 more source

