Results 101 to 110 of about 400,898 (240)

Benchmarking commercial large language models for gene–disease–phenotype extraction from full‐text human genetics literature

Quantitative Biology, Volume 14, Issue 4, December 2026.
Abstract Manual curation of gene–disease–phenotype relationships from the human genetics literature is a persistent bottleneck for maintaining its bioinformatics databases. Whereas large language models (LLMs) offer a promising alternative, there is currently no systematic benchmark that evaluates whether state‐of‐the‐art commercial LLMs can perform ...
Danqing Yin, Matthew Ka Siu Leung, Darren Wan Ho Pun, Fiona Haixin Chen, Julie Yujin Kwon, Xinyi Lin, Joshua W. K. Ho   +6 more
wiley   +1 more source

Weighted Single‐Step GWAS Reveals Genetic Mechanisms Underlying Pregnancy Loss in Early Nellore Heifers

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Pregnancy loss (PL) affects reproductive efficiency in beef cattle, yet its genetic architecture remains poorly understood in Bos indicus populations. Here, PL was defined as failure from pregnancy diagnosis to calving, capturing a window approximately 60 days after the breeding season.
Flávia C. Bis, Nedenia Bonvino Stafuzza, Elisângela Chicaroni de Mattos, Angélica Simone Cravo Pereira, José Bento Sterman Ferraz, Fernando Baldi, Sabrina T. Amorim   +6 more
wiley   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Primary Repair of a Jejunal Atresia With Christmas Tree Deformity in a Preterm Infant

Clinical Case Reports
Although uncommon in the general population, jejunoileal atresia (JIA) is a common cause of intestinal obstruction in infants. This congenital anomaly may cause a substantial reduction in intestinal length, enhancing the likelihood of short bowel ...
Dennis Machaku, Jastin Kijazi, Joachim Magoma, Mkunde Chambo, Timon Shillah, David Msuya   +5 more
doaj   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3586-3597, October 2026.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

MicrotiaGPT: Appraisal of Microtia Care Recommendations From an Artificially Intelligent Chatbot

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
ABSTRACT Objective Evaluate the accuracy, comprehensiveness, and similarity to provider response of ChatGPT‐4o in providing patient education regarding microtia and aural atresia management. Methods Ten standardized inquiries were created across three domains (General Information, Hearing/Anatomy, Treatment Decision‐Making) and entered into ChatGPT‐4o.
Oluwatobiloba Ayo‐Ajibola, Simon Park, Beth Osterbauer, Krystina Kallemeyn, Gabriel Gomez   +4 more
wiley   +1 more source

Variability in Fecundity–Body Size Relationships for Atlantic Salmon Associated With Body Condition and Life History

Fisheries Management and Ecology, Volume 33, Issue 5, Page 1002-1017, October 2026.
ABSTRACT While body size is the primary driver of fecundity, other factors may contribute to variation in these relationships. Anadromous populations of Atlantic salmon (Salmo salar) have diverse life histories, and fisheries management relies on accurate fecundity estimates.
Tara L. Imlay, Cindy Breau, Julien April, J. Brian Dempson, John Hayward, Jason LeBlanc, Jenny E. Reid, David Roth, Jamie T. Vallis, Travis E. Van Leeuwen, Laura K. Weir   +10 more
wiley   +1 more source

Intestinal Atresia Type IV and its Complications: Case Presentation

La atresia intestinal es una malformación congénita poco frecuente que se caracteriza por la interrupción o discontinuidad del tracto gastrointestinal.
Calero Correa, Aliz Janeth, Casanova Castillo, Mónica Mariana, Tene Carrillo, Cecilia Ximena, Massache Young, Cecilia Edith   +3 more
core   +1 more source

Ductular Reaction Underlies Development of Portal Hypertension in Biliary Atresia

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background & Aims As better understanding of pathophysiology and reliable predictors for portal hypertension (PH) are needed, we investigated how histological ductular reaction (DR) and liver fibrosis predict PH in biliary atresia (BA). Methods 60 BA patients treated between 1987 and 2024 at Helsinki University Hospital were enrolled. Patients
Petriina Luokkala, Maria Hukkinen, Iiris Nyholm, Nelli Sjöblom, Mikko P. Pakarinen   +4 more
wiley   +1 more source

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie, Mengyan Zhu, Zhongxian Zhu, Jiaqi Tang, Ruyi Zhang, Zequan Ding, Junzhi Li, Zhongluan Wu, Paul Kwong Hang Tam, Qianghu Wang, Vincent Chi Hang Lui, Yankai Xia, Weibing Tang   +12 more
wiley   +1 more source