The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez+8 more
wiley +1 more source
Energy metabolism and the intestinal barrier: implications for understanding and managing intestinal diseases. [PDF]
Chen S+11 more
europepmc +1 more source
Adherens junction proteins on the move-From the membrane to the nucleus in intestinal diseases. [PDF]
Lessey LR+3 more
europepmc +1 more source
Hypobetalipoproteinemia with accumulation of an apoprotein B-like protein in intestinal cells. Immunoenzymatic and biochemical characterization of seven cases of Anderson's disease. [PDF]
M.E. Bouma+4 more
openalex +1 more source
Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang+13 more
wiley +1 more source
Machine learning-based diagnostic model for neonatal intestinal diseases in multiple centres: a cross-sectional study protocol. [PDF]
Zhao Q+9 more
europepmc +1 more source
Elafin and its precursor trappin-2: What is their therapeutic potential for intestinal diseases? [PDF]
Deraison C+4 more
europepmc +1 more source
Sensitization to epithelial antigens in chronic mucosal inflammatory disease. Characterization of human intestinal mucosa-derived mononuclear cells reactive with purified epithelial cell-associated components in vitro. [PDF]
James K. Roche+2 more
openalex +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Mechanisms of Insulin Signaling as a Potential Therapeutic Method in Intestinal Diseases. [PDF]
Jarmakiewicz-Czaja S+3 more
europepmc +1 more source