Results 291 to 300 of about 9,941,870 (340)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

open access: yesAdvanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong   +7 more
wiley   +1 more source

Glutathione and Laccase Dual‐Responsive Lignin Nanocarriers Inspired by Host‐Pathogen Interactions for Fungicide Delivery

open access: yesAdvanced Functional Materials, EarlyView.
Discover bio‐inspired fungicide‐loaded lignin nanocarriers that mimic host‐pathogen interactions, unleashing targeted fungicide release in response to glutathione and laccase. These innovative biobased nanocarriers promise superior crop protection, with increased photostability, enhanced foliar retention, and enabling bidirectional translocation for a ...
Wenlong Liang   +4 more
wiley   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

open access: yesAdvanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao   +6 more
wiley   +1 more source

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