Results 81 to 90 of about 846,419 (356)

V-037 PARASTOMAL MESH INFECTIONS WITH INTESTINAL FISTULA: 2 RARE SURGICAL CASES AND HOW WE FIXED THEM [PDF]

open access: bronze, 2022
Camillo Leonardo Bertoglio   +5 more
openalex   +1 more source

Surgical Management of Inguinal Hernias at Bugando Medical Centre in Northwestern Tanzania: Our Experiences in a Resource-Limited Setting. [PDF]

open access: yes, 2012
Inguinal hernia repair remains the commonest operation performed by general surgeons all over the world. There is paucity of published data on surgical management of inguinal hernias in our environment.
AN Kingsnorth   +38 more
core   +2 more sources

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun   +8 more
wiley   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

An unusual case of hematemesis: Spontaneous reno-duodenal fistula

open access: yesJournal of Digestive Endoscopy, 2014
Different diseases may cause gastrointestinal bleeding. A fistula infrequently manifest with severe intestinal bleeding, when excluding those directly involving vascular structures.
Vincenzo De Francesco   +3 more
doaj   +1 more source

Tube choledochoureterostomy: A simple method for bile diversion [PDF]

open access: yes, 1990
A technique of bile diversion by tube choledochoureterostomy has been devised for the purpose of studying the role of bile in the intestinal absorption of drugs. This method was used in six dogs. No technical difficulties or major complications developed,
Andrews W   +12 more
core   +1 more source

Curved Bistable Origami‐Inspired Flexible Transcatheter Mitral Valve Clamping

open access: yesAdvanced Science, EarlyView.
A lightweight bistable curved origami dilator combines reversible deformation and high stability, offering a promising solution for minimally invasive mitral valve repair. Abstract Curved origami exhibits remarkable potential for minimally invasive medical applications owing to its unique geometric programmability and mechanical tunability. Building on
Siyu Gao   +4 more
wiley   +1 more source

Operative strategy for fistula-in-ano without division of the anal sphincter [PDF]

open access: yes, 2013
We would like to thank Mr ER MacDonald for his contribution in data collection during the early years of the study. The material in this paper was presented as a poster at the annual meeting of the American Society of Colon and Rectal Surgeons held in ...
Abbas MA   +8 more
core   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

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