Results 31 to 40 of about 74,837 (261)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Prebiotics and Intestinal Flora
Bioscience and Microflora, 2002 During the past 5 decades, research in intestinal flora has made rapid progress, which includes the following: (1) development of a comprehensive culture method; (2) establishment of the classification and identification of intestinal anaerobic bacteria; (3) accumulation of microecological evidence and the beneficial and harmful functions of intestinal
openaire +2 more sources
Intestinal flora, probiotics, and cirrhosis
Annals of Hepatology, 2008 Intestinal microflora constitutes a symbiotic ecosystem in permanent equilibrium, composed mainly of anaerobic bacteria. However, such equilibrium may be altered by daily conditions as drug use or pathologies interfering with intestinal physiology, generating an unfavorable environment for the organism.
Ignacio Guerrero Hernández +3 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Comparison of Intestinal Microbiota of Blue Fox before and after Weaning
AnimalsIntestinal flora plays an important role in maintaining the internal stability and health of the intestine. Currently, intestinal microbes are considered an important “organ” but are mostly ignored by people.
Hang Su +6 more
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Studies on the intestinal flora [PDF]
Gut, 1969 The type and distribution of bacteria in the jejunal juice of patients with a variety of gastrointestinal conditions that might affect the small intestinal flora were examined. Bacterial colonization of the jejunum defined, in this context, as the occurrence of a bile salttolerant flora consisting of both aerobic and anaerobic ...
B S, Drasar, M, Shiner
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
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Gut health: The results of microbial and mucosal immune interactions in pigs
Animal Nutrition, 2021 There are a large number of microorganisms in the porcine intestinal tract. These microorganisms and their metabolites contribute to intestinal mucosal immunity, which is of great importance to the health of the host.
Jie Peng, Yimei Tang, Yanhua Huang
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Frontiers in PharmacologyHypertension is a common disease; however, it is more prevalent in older adults, and its prevalence is increasing in younger populations. Numerous studies have revealed that hypertension and the composition and functionality of the intestinal flora are ...
Wenjun Chen +9 more
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