Results 131 to 140 of about 198,094 (268)

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Correction: The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats. [PDF]

Front Mol Biosci
Liu Z, Li P, Zhang Y, Zhao S, Gao W.
europepmc   +1 more source

Modified Diatomaceous Earth in Heparin Recovery from Porcine Intestinal Mucosa. [PDF]

Molecules, 2023
Das A, Khambhati DP, Longoria ND, Tabibi A, Davachi SM, Dimas K, Laurencin Y, Carmona L, Avalos PZ, Karimi Abdolmaleki M.   +9 more
europepmc   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Regulation of hydrogen and oxidative stress in treating intestinal mucosa from ulcerative colitis. [PDF]

Int J Pharm X
Yu N, Xu J, Fan J, Gao H, Wu T, Zhu Y, Xu J, Li X, Xu H, Lu X.   +9 more
europepmc   +1 more source

Activation of P2Y1R impedes intestinal mucosa repair during colitis. [PDF]

Int J Biol Sci, 2023
Huan Q, Peng J, Chang Y, Zhang Q, Xing T, Jiang D, Chen W, Shen X, Bian Z, Xiao H.   +9 more
europepmc   +1 more source

Hollow Cu2O Nanozymes Enhance Probiotic Therapy for Colitis via Redox Homeostasis and TXNIP/NLRP3 Inflammasome Inhibition

Advanced Science, EarlyView.
Hollow cuprous oxide (H‐Cu2O) nanozymes feature enlarged catalytic surfaces for superior reactive oxygen species (ROS) scavenging. By efficiently neutralizing mucosal ROS, H‐Cu2O directly suppresses the TXNIP/NLRP3 inflammasome axis and restores intestinal epithelial barrier integrity.
Guangzhao Wang, Jialing Cao, Pengfei Li, Yujie Wang, Shiqi Lu, Kangliang Sheng, Shan Gao, Yongzhong Wang   +7 more
wiley   +1 more source

Impaired Iron-Copper Metabolic Axis in Human Intestinal Mucosa After Roux-en-Y Gastric Bypass: A Prospective Transcriptomic Study Using Double-Balloon Enteroscopy. [PDF]

Obes Surg
Shimizu C, Waitzberg DL, Torrinhas RS, Heymsfield SB, Passadore MD, Sala P.   +5 more
europepmc   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring. [PDF]

Exp Biol Med (Maywood)
Yanamadala Y, Muthumula CMR, Gokulan K, Karn K, Sutherland V, Cunny H, Santos JH, Khare S.   +7 more
europepmc   +1 more source