Results 181 to 190 of about 361,975 (346)

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Abundance of bacteria and histopathologic findings in the small intestinal mucosa of dogs with chronic inflammatory enteropathies. [PDF]

open access: yesPLoS One
Queiroz-Machado CRR   +12 more
europepmc   +1 more source

Biodegradable Adhesive Systems for Bio‐Integrated Applications

open access: yesAdvanced Science, EarlyView.
Biodegradable adhesives provide temporary yet reliable adhesion while degrading into safe, non‐toxic by‐products under physiological or environmental conditions. This review summarizes recent developments in physical and chemical adhesion mechanisms—including hydrogen bonding, catechol chemistry, amine‐carboxyl coupling, and emerging diazirine and urea
Won Bae Han   +6 more
wiley   +1 more source

Regulation of hydrogen and oxidative stress in treating intestinal mucosa from ulcerative colitis. [PDF]

open access: yesInt J Pharm X
Yu N   +9 more
europepmc   +1 more source

Modified Diatomaceous Earth in Heparin Recovery from Porcine Intestinal Mucosa. [PDF]

open access: yesMolecules, 2023
Das A   +9 more
europepmc   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

Activation of P2Y1R impedes intestinal mucosa repair during colitis. [PDF]

open access: yesInt J Biol Sci, 2023
Huan Q   +9 more
europepmc   +1 more source

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