Results 181 to 190 of about 359,042 (297)

Effects of faecal microbiota transplantation on the small intestinal mucosa in systemic sclerosis. [PDF]

open access: yesRheumatology (Oxford), 2023
Strahm N   +12 more
europepmc   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang   +11 more
wiley   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li   +12 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Uncovers Immunological Phenotypes Predictive of Combinatorial Immunotherapy Response in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Current understanding of gastric cancer immunity remains inadequate, leading to suboptimal immunotherapy outcomes. This study introduces a novel tumor immune microenvironment classification system (Inflamed, Desert, and Excluded), advancing traditional histopathological or molecular subtyping toward a functional immunological framework.
Jianchao Wang   +14 more
wiley   +1 more source

The intestinal mucosa-associated microbiota in IBD-associated arthritis displays lower relative abundance of <i>Roseburia intestinalis</i>. [PDF]

open access: yesGut Microbes
Alizadeh M   +12 more
europepmc   +1 more source

Immunometabolic Profile Associated with Progressive Damage of the Intestinal Mucosa in Adults Screened for Colorectal Cancer: Association with Diet. [PDF]

open access: yesInt J Mol Sci, 2023
González C   +11 more
europepmc   +1 more source

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