Results 241 to 250 of about 658,048 (298)

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li   +3 more
wiley   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

open access: yesAdvanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang   +12 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

open access: yesAngewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej   +20 more
wiley   +2 more sources

Boosting Charge Storage in Ferri/Ferrocyanide‐Based Alkaline Redox Flow Batteries

open access: yesAngewandte Chemie, EarlyView.
By modifying the solvation environment, cation engineering through Li+ substitution of traditional K+ or Na+ boosts the alkaline solubility of the ferri/ferrocyanide catholyte redox couple, providing a viable pathway to overcome the long‐standing challenge of energy density limitations for aqueous redox flow batteries (RBFs).
Mahla Sarfaraz Khabbaz   +6 more
wiley   +1 more source

[Intestinal parasites].

open access: yesPrzeglad epidemiologiczny, 1978
Z, Dymowska, K, Zembrzuski
openaire   +1 more source

Parasitic infections of the intestine

Current Opinion in Infectious Diseases, 2001
Intestinal protozoal infections cause significant disease not only in the tropics but also in immunocompromised hosts and returning travellers in the developed world. Precise diagnosis of protozoal intestinal infection by microscopy can be difficult.
H, Schuster, P L, Chiodini
openaire   +2 more sources

Intestinal parasitic infection

Abdominal Imaging, 2007
In general, gastrointestinal tract is the primary involvement site of parasites during their life cycle. In this article, we will describe amebiasis, ascariasis, and anisakiasis among the many common intestinal parasitic diseases. We will review the epidemiology, life cycles, clinical manifestations and complications, and illustrate detailed imaging ...
Mi-Suk, Park   +3 more
openaire   +2 more sources

Intestinal parasitic infections

Current Opinion in Gastroenterology, 1999
Our understanding of the biology of several intestinal parasites has progressed considerably in the past year, especially in the area of molecular biology. Information from molecular and genetic analyses has been used increasingly to improve understanding of pathogenesis, to apply improved diagnostic methods, and to seek new vaccination strategies ...
A, Das, E P, Variyam
openaire   +2 more sources

Intestinal parasites

Primary Care: Clinics in Office Practice, 2002
Although safe and efficacious broad-spectrum antiparasitic drugs have been developed, their availability for use in mass-treatment programs and for individual treatment worldwide can be limited by economic resources, existing manufacturing and distribution networks, and national regulations.
openaire   +2 more sources

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