Results 261 to 270 of about 127,475 (345)

Contrasting Reproductive and Early Life‐History Strategies in Recently Diverged Octocoral Species (Paramuricea spp.)

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
The two color morphs of the Iberian–Atlantic Paramuricea complex show little genetic divergence, and their species boundaries have remained unclear. By analyzing gametogenesis, spawning timing, fertilization environment, and early life‐history traits, we reveal strong prezygotic barriers and divergent developmental and dispersal strategies between the ...
Christina Egger   +10 more
wiley   +1 more source

An Unusually Deep Corallimorph Barren on a Remote Coral Reef in the South‐Central Red Sea

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
We report a corallimorph barren on a remote coral reef in the southern Red Sea. Unlike previous studies that show corallimorphs prefer shallow habitats in disturbed conditions, corallimorphs were absent in the shallow areas of the reef but dominated the substrate from 15 to at least 30 m depth. The cause of this dominance is unclear, as the uninhabited
Walter A. Rich   +7 more
wiley   +1 more source

Attenuation of the CpG island methylator phenotype and lack of WNT signalling activation restrains Kras mutant intestinal neoplasia. [PDF]

open access: yesBr J Cancer
Fennell L   +10 more
europepmc   +1 more source

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

open access: yesExploration, Volume 6, Issue 2, April 2026.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu   +10 more
wiley   +1 more source

Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
Proteomic profiling of tissue explant‐ and plasma‐derived extracellular vesicles identified colon adenocarcinoma‐associated and healthy‐associated EV proteins. A 10‐protein EV panel enabled highly sensitive blood‐based detection of colon adenocarcinoma, showed marked postoperative changes, and retained performance in an independent validation cohort ...
Yura Seo   +33 more
wiley   +1 more source

Outcome Modification and Disclosure Practices in Sinonasal Clinical Trials: A Registry‐Based Cross‐Sectional Analysis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objectives To characterize the frequency, nature, timing, and transparency of prespecified outcome modifications in interventional trials for inflammatory sinonasal disease registered on ClinicalTrials.gov. Methods We identified interventional trials for inflammatory sinonasal disease registered on ClinicalTrials.gov with published primary ...
Kohl Kirby   +9 more
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

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