Results 111 to 120 of about 11,580 (206)

Enhancing Reaction Kinetics and Structural Control in N‐Carboxyanhydride (NCA) Polypeptide Synthesis by Structurally Tuned Azamacrocyclic Ligands

Angewandte Chemie, EarlyView.
Azamacrocycles provide a tunable platform for rapid N‐carboxyanhydride (NCA) Ring‐Opening Polymerization (ROP). Changing the methylation pattern switches the macrocycle from an external catalyst (N14Me3) to a covalent initiator‐catalyst (IniCat, N14Me1), delivering controlled polypeptide growth under open‐vessel conditions.
Paulina Maksym, Adam Gorczynski, Robert D. Murphy, Gianluca Bartolini Torres, Roksana Wygoda, Karol Garbaczewski, Giuseppe Forte, Giuseppe Consiglio, Yixuan Chen, Sébastien Perrier, Andreas Heise   +10 more
wiley   +2 more sources

Vertical NAND Flash Memory‐Based Bayesian Neural Networks With Intrinsic Gaussian Weight Sampling

Advanced Intelligent Systems, EarlyView.
Commercial vertical NAND flash memory supports Bayesian neural networks by using paired cells to produce bell‐shaped weight distributions. Read voltage controls their spread without additional memory cells or changes to the array structure. Simulations based on device measurements demonstrate improved uncertainty estimation and accuracy gains of up to ...
Sung‐Ho Park, Mingyun Oh, Dongbeen Shin, Jaehyeon Kim, Jonghyun Ko, Jiseong Im, Yeongheon Yang, Gyuweon Jung, Jong‐Ho Lee   +8 more
wiley   +1 more source

Correction: Late-onset mitochondrial encephalomyopathy lactic acidosis and stroke-like episodes with chronic intestinal pseudo-obstruction: a case-based review. [PDF]

Front Mol Biosci
Zhang L, Lin J, Li F, Jia Y, Li J, Wang X.   +5 more
europepmc   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

Advanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò, Semproni Federica, Maselli Martina, Colli Andrea, Cianchetti Matteo, Ciuti Gastone, Stefanini Cesare, Menciassi Arianna   +7 more
wiley   +1 more source

Accessibility and Alignment of Trans‐Cleavage Substrates Modulate the Kinetics of Cas12a Ribonucleoprotein

Angewandte Chemie, EarlyView.
Two key binding events that collectively determine the catalytic efficiency of trans‐cleavage: (1) the substrate passing through the gap between the REC and NUC domains, determined by Kpass, and (2) the alignment of the substrate with the catalytic triad of the ribonucleoprotein, determined by Kalign.
Jianyu Hu, Wei Feng, Hongquan Zhang, X. Chris Le   +3 more
wiley   +2 more sources

Analysis of Diagnosis and Treatment of Active Lupus Enteritis Accompanied by Intestinal Pseudo-Obstruction as the Initial Manifestation: A Case Report and Literature Review. [PDF]

Case Rep Gastrointest Med
Zhuang W, Ji M, Xu P, Wang L, Jing J, Pan W, Zhang C.   +6 more
europepmc   +1 more source

Preferential trading in agriculture: New insights from a structural gravity analysis and machine learning

American Journal of Agricultural Economics, EarlyView.
Abstract Preferential trade agreements (PTAs) contain various non‐tariff provisions, yet identifying their trade effects remains challenging because these commitments are high‐dimensional and strongly correlated within agreements. We estimated a theory‐consistent structural gravity model with domestic flows for 26 agricultural subsectors over 1988–2017
Dongin Kim, Sandro Steinbach
wiley   +1 more source

Oxygen‐Tolerant, Controlled Synthesis of Degradable and Water‐Soluble Poly(Vinyl Amide)s via Radical Ring‐Opening Copolymerization of Cyclic Dithiothreitol

Angewandte Chemie, EarlyView.
Oxygen‐tolerant photoinduced electron/energy transfer reversible addition–fragmentation chain transfer (PET‐RAFT) polymerization enables the controlled radical ring‐opening (rROP) copolymerization of cyclic dithiothreitol (cDTT) with less‐activated vinyl monomers, affording degradable polymers with predictable molecular weights, low dispersities, and ...
Alessandro Magro, Ivan O. Levkovsky, Hironobu Murata, Francesca Lorandi, Edmondo M. Benetti, Krzysztof Matyjaszewski   +5 more
wiley   +2 more sources

SLE-associated intestinal pseudo-obstruction: a case report and analysis of 43 cases. [PDF]

Front Immunol
Long T, Li J, Li SG, Zhang J, Zhang L, Zou Y, Yu R, Zhang Y.   +7 more
europepmc   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source