Results 71 to 80 of about 18,592 (297)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

A unique case of late-onset CIPO caused by a missense mutation in the long isoform of FLNA

Frontiers in Genetics
Mutations in the filamin A (FLNA) gene cause a broad range of disorders, affecting musculoskeletal, nervous, vascular, and gastrointestinal systems, collectively known as filaminopathies.
Ilaria D’Amato, Enrico Ganguzza, Enrico Ganguzza, Guido Basilisco, Alessia Strippoli, Erika Salvi, Elkadia Mehmeti, Federica Chiappori, Grazia Devigili, Maurizio Vecchi, Maurizio Vecchi, Giuseppe Lauria, Giuseppe Lauria, Margherita Marchi   +13 more
doaj   +1 more source

Interphase Self‐Optimization Enables Stable Magnesium Anode in Hydrogel Electrolyte

Advanced Materials, EarlyView.
Based on a MgCl2 hydrogel electrolyte, we identify a tridentate chelant additive to construct a magnesium oxychloride interphase on Mg metal anodes. This self‐optimized interphase enables low‐resistance Mg2+ stripping/plating, resulting in much elongated cycling life of 600 h with 0.24 V nucleation overpotential.
Xinyuan Zhang, Hengyue Xu, Heng Jiang, Fei Du, Hong Jin Fan   +4 more
wiley   +1 more source

Chronic idiopathic intestinal pseudo-obstruction treated with jejunostomy: case report and literature review

São Paulo Medical Journal
CONTEXT: Chronic idiopathic intestinal pseudo-obstruction is a very rare condition. CASE REPORT: This study describes a male patient who had presented obstructive symptoms for 24 years.
Carlos Renato dos Reis Lemos, Pedro Popoutchi, Rogério Serafim Parra, Omar Féres, José Joaquim Ribeiro da Rocha   +4 more
doaj   +1 more source

Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction [PDF]

, 2013
The retinoblastoma 1 (RB1) tumor suppressor is a critical regulator of cell cycle progression and development. To investigate the role of RB1 in neural crest–derived melanocytes, we bred mice with a floxed Rb1 allele with mice expressing Cre from the ...
Carreira, J. William Harbour, Luke A. Wiley, Lundberg, Marino, Michael Shoykhet, Ming Fu, Newgreen, Olga A. Agapova, Robert O. Heuckeroth, Solange Landreville   +10 more
core   +2 more sources

Integrating ZnO/Ag2O@g‐C3N4‐Based Nanocomposites Into a Carrageenan Matrix to Efficiently Remove Heavy Metals From Water

Advanced Materials Interfaces, EarlyView.
ABSTRACT This research focused on characterizing graphitic carbon nitride (g‐C3N4) nanocomposites incorporated with ZnO and Ag2O nanoparticles, and carrageenan to remove heavy metals. The ZnO/Ag2O@ g‐C3N4 and ZnO/Ag2O/g‐C3N4@Carr nanocomposites demonstrated thermal stability of 97.40% (108.81°C) and 82.80% (188.99°C) for TGA.
Feziwe B. Mamba, Bhekani S. Mbuli, James Ramontja   +2 more
wiley   +1 more source

Diagnosis and Treatment of Small Intestinal Bacterial Overgrowth [PDF]

, 2015
Small Intestinal Bacterial Overgrowth (SIBO) is a clinical condition, in which excess amounts of bacteria are found in small intestine. SIBO occurred when normal homeostatic mechanism which control enteric bacteria population disrupted.
Fauzi, A. (Achmad), Nababan, T. (Toman)
core   +2 more sources

Relationship of Dye Adsorption Onto Biomass Activated Carbon Mixed Matrix Ultrafiltration: A Mass Transfer Model Study

Advanced Materials Interfaces, EarlyView.
This study explored dye molecule adsorption from water, focusing on activated carbon in polymer membranes for purifying low‐quality water. Polyvinylidene fluoride (PVDF) membranes showed enhanced removal efficiency of methylene blue (MB) from 89.29% to 98.33% with biomass‐activated carbon (BAC).
Khairul Anwar Mohamad Said, Shaiza Asif, Siti Zahara May Abdullah, Ibrahim Yakub, Harunal Rejan Ramji, Md Rezaur Rahman   +5 more
wiley   +1 more source

VALUE OF PLAIN ABDOMINAL RADIOGRAPH, ULTRASOUND AND COMPUTERIZED TOMOGRAPHY IN THE DIAGNOSIS OF INTESTINAL OBSTRUCTION

The Iraqi Journal of Medical Sciences, 2017
Background: The diagnosis of mechanical intestinal obstruction is sometimes very challenging especially in the absence of previous abdominal surgery or obstructed hernia and there are limited studies comparing or evaluating the usefulness of plain ...
Nawfal K. Salih
doaj   +6 more sources

Ogilvie Syndrome in a Refractory Germ Cell Tumor Treated with Vinblastine, Ifosfamide and Cisplatin Regimen

Case Reports in Oncology, 2020
Ogilvie syndrome or intestinal pseudo-obstruction is a clinical syndrome characterized by autonomic imbalance affecting peristalsis of colon leading to obstructive signs and symptoms. The etiologies commonly implicated are drugs affecting the cholinergic
Hrishi Varayathu, Mansi Sandip Shah, Vinu Sarathy, Beulah Elsa Thomas, Vinayak Munirathnam, Shivakumar Swamy Shivalingappa, Radheshyam Naik   +6 more
doaj   +1 more source