Results 211 to 220 of about 617,309 (289)

Demulsifying agent simplified model for offshore oil wells

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract This article addresses key challenges in offshore petroleum production caused by multiphase flow instabilities, such as slug flow and emulsion formation. Traditionally, severe slugging is mitigated by increasing wellhead backpressure through partial choke valve closure. In this context, a simplified dynamic model—the fast offshore wells model (
Fernanda Bernardi de Souza   +5 more
wiley   +1 more source

Occurrence of severe slugging in oil production lines and mitigation methods: A numerical simulation approach using ALFAsim®

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Severe slugging represents a major challenge in offshore production systems, potentially compromising operational stability and the integrity of installations. Although established simulators such as OLGA® are widely used for its analysis, there is a gap in the literature regarding the application of the one‐dimensional simulator ALFAsim® for ...
Wayne Gabriel Nóbrega Firme   +4 more
wiley   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart   +6 more
wiley   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul   +5 more
wiley   +1 more source

Hiding in Plain Sight: A Case of Intestinal Tuberculosis Masquerading as Benign Lower GI Bleeding. [PDF]

open access: yesCase Rep Gastrointest Med
Otom L   +6 more
europepmc   +1 more source

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