Results 31 to 40 of about 35,983 (255)

First description of shark Isistius brasiliensis (Dalatiidae) in the waters of Russia

open access: yesИзвестия ТИНРО, 2015
Description of rare shark Isistius brasiliensis caught off southern Kuril Islands on July 18, 1978. Morphometric parameters are presented, including counts of dorsal and caudal vertebras, teeth rows, mitral valves, and intestinal helical valve coils.
Vladimir N. Dolganov
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli   +10 more
wiley   +1 more source

OntOMat: Toward Ontology‐Based Product and Process Design Engineering and Optimization Solutions Fueling Circular Value Chains

open access: yesAdvanced Engineering Materials, EarlyView.
The OntOMat ontology establishes a structured framework for polymer matrix fiber reinforced composite materials, integrating manufacturing processes, characterization methods, and multiscale design through the VDI/VDE 3682 formalized process description standard.
Nicolas Christ   +19 more
wiley   +1 more source

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

open access: yesAdvanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia   +12 more
wiley   +1 more source

An Electrowetting Pump

open access: yesAdvanced Functional Materials, EarlyView.
A tubular electrowetting pump moves alternating droplets through a millimeter‐wide channel in discrete, reversible steps, functioning as a fluidic stepper motor. With no moving parts and electrodes insulated from the liquid, it delivers silent, accurate flow. Flexibility allows the pump to be woven directly into textiles for wearable, medical, and soft‐
Robert Hennig, Herbert Shea
wiley   +1 more source

3D Hydrodynamic Flow Lithography

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Continuous‐ and stop‐flow lithography are widely used to fabricate multi‐dimensional microstructures whose cross‐sectional morphology is dictated by the flow profile of multiple co‐flowing streams. Here, we introduce three‐dimensional hydrodynamic flow lithography (3D HFL), a platform for programmable generation of multi‐layered flow profiles ...
Yiying Zou   +5 more
wiley   +1 more source

The ileocecal valve in transabdominal ultrasound Part 1: Sonographic anatomy and technique

open access: yesJournal of Ultrasonography
The ileocecal valve is a part of the gastrointestinal tract that separates two intestinal segments differing in both anatomy and function. Dysfunction or surgical removal of the valve usually results in the development of small intestinal bacterial ...
Smereczyński Andrzej   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Imperatorin Alleviates Intestinal Fibrosis by Suppressing AIM2-mediated GSDMD Pyroptosis in MacrophagesSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology
Background & Aims: Over-activation of pyroptosis, recently reidentified as Gasdermin D (GSDMD)-mediated proinflammatory cell death, results in severe inflammation-related disorders.
Sheng Li   +13 more
doaj   +1 more source

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