Results 61 to 70 of about 35,983 (255)

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Gallstone ileus resulting in strong intestinal obstruction

São Paulo Medical Journal
Mechanic intestinal obstruction, caused by the passage of biliary calculus from vesicle to intestine, through fistulization, although not frequent, deserve study due to the morbi-mortality rates.
Israel Szajnbok, Fernando Lorenzi, Aldo Junqueira Rodrigues Jr., Luis Fernando Correa Zantut, Renato Sérgio Poggetti, Elian Steinman, Dario Birolini   +6 more
doaj   +1 more source

Massive Lipomatosis of the Small Intestine Causing Intussusception

Case Reports in Gastrointestinal Medicine, 2019
Lipomatosis is a rare condition characterized by diffuse, unencapsulted adipose tissue deposition. Intestinal involvement is rare, and presentation as intussusception is rarer still. We report a 40-year-old man who presented with abdominal pain and fecal
Michael Pagacz, Irvin Willis, John Alexis   +2 more
doaj   +1 more source

Atypical perioperative management for duodenal obstruction in an infant with heterotaxy syndrome: a case report

JA Clinical Reports, 2018
Background Heterotaxy syndrome (HS) is characterized by a wide variety of cardiac and extra-cardiac malformations, including pulmonary valve stenosis, interruption of the inferior vena cava, total anomalous pulmonary venous connection (TAPVC), asplenia ...
Hirofumi Obinata, Shinichi Nishibe, Yoko Ishihara   +2 more
doaj   +1 more source

Discovering Early‐Stage Gas Generation Kinetics Enables Thermal Runaway Early Warning in Lithium‐Ion Batteries

Advanced Science, EarlyView.
Operando gas diagnostics reveal a previously unrecognized chemical activation (CA) stage during thermal runaway in lithium‐ion batteries. A physics‐informed gas generation kinetics network (GGKNet) is developed to reconstruct reaction pathways and physical models automatically.
Jiabo Zhang, Qianzhen Guo, Shuaiqi Liu, Shuai Li, Xianghao Kong, Dong Han, Zhen Huang   +6 more
wiley   +1 more source

A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping

Advanced Science, EarlyView.
This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo, Hui Ji, Ruidong Hong, Songlin Nie, Fanglong Yin, Zhonghai Ma   +5 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Gallstone ileus as a cause of upper intestinal obstruction

São Paulo Medical Journal
Gallstone ileus, a mechanical intestinal obstruction caused by the passage of a gallstone into the intestinal lumen through a fistula, although not common, deserves to more carefully studied due to its morbidity and mortality.
Israel Szajnbock, Fernando Lorenzi, Aldo Junqueira Rodrigues Jr., Luis Fernando Correa Zantut, Renato Sérgio Poggetti, Eliana Steinman, Dario Birolini   +6 more
doaj   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source