Results 61 to 70 of about 596,223 (286)
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]
, 2015 In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
core +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Transplantation of the small intestine: the pathologist's perspective. [PDF]
, 1990 Small-bowel transplantation is now ready for clinical trials. The surgical techniques and methods for immunosuppression and monitoring bowel status have been developed in animal models over the past 30 years.
Banner, B +4 more
core
Small Intestine in Psoriasis [PDF]
BMJ, 1967 Twenty-three female and 19 male patients were studied. Their ages ranged from 15 to 72 years. The total length of history of psoriasis ranged from 3 weeks to 50 years, and the duration of the most recent episode from 1 week to 20 years. All patients had been admitted to hospital for treatment and were studied consecutively, apart from a few who ...
Sam Shuster +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Neuroendocrine tumor of the small intestine
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019 Intestinal carcinoid is a type of neuroendocrine neoplasia of the small intestine that rarely presents with clinical manifestations. In some cases, it has an aggressive and highly symptomatic behavior, so the clinical suspicion must be high to make an ...
Javier Martínez-Navarro +2 more
doaj
Gastrointestinal Stromal Tumors of Small Intestine
The Surgery Journal, 2019 Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj +1 more source
Asian Pacific Journal of Cancer Biology, 2022 Background: Intussusception refers to telescoping of one intestinal segment and its mesentery into an adjacent intestinal loop. It is a rather frequent entity in infants with an excellent prognosis.
Maisa Hashem Mohammed
doaj +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source