Results 71 to 80 of about 793,315 (309)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Electromagnetic radiation from ingested sources in the human intestine between 150 MHz and 1.2 GHz [PDF]

open access: yes, 2003
The conventional method of diagnosing disorders of the human gastro-intestinal (GI) tract is by sensors embedded in cannulae that are inserted through the anus, mouth, or nose.
Chirwa, L.C.   +3 more
core   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Gastrointestinal Stromal Tumors of Small Intestine

open access: yesThe Surgery Journal, 2019
Gastrointestinal stromal tumor (GIST) is defined as mesenchymal tumors of the gastrointestinal tract expressing proto-oncogene protein CD117. They are the most common sarcomatous tumors of the gastrointestinal tract.
Tanweerul Huda, Mahendra Pratap Singh
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Neuroendocrine tumor of the small intestine

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Intestinal carcinoid is a type of neuroendocrine neoplasia of the small intestine that rarely presents with clinical manifestations. In some cases, it has an aggressive and highly symptomatic behavior, so the clinical suspicion must be high to make an ...
Javier Martínez-Navarro   +2 more
doaj  

A Submucosal Lipoma of Small Intestine as an Unpredictable Cause of Intussusception and Intestinal Obstruction; A Case Report and Literature Review

open access: yesAsian Pacific Journal of Cancer Biology, 2022
Background: Intussusception refers to telescoping of one intestinal segment and its mesentery into an adjacent intestinal loop. It is a rather frequent entity in infants with an excellent prognosis.
Maisa Hashem Mohammed
doaj   +1 more source

Asymmetric Fluid Flow in Helical Pipes Inspired by Shark Intestines [PDF]

open access: yesProc. Natl. Acad. Sci. U.S.A. 121 (40) e2406481121 (2024)
Unlike human intestines, which are long, hollow tubes, the intestines of sharks and rays contain interior helical structures surrounding a cylindrical hole. One function of these structures may be to create asymmetric flow, favoring passage of fluid down the digestive tract, from anterior to posterior.
arxiv   +1 more source

Gastrointestinal Polyps and Tumors Detection Based on Multi-scale Feature-fusion with WCE Sequences [PDF]

open access: yesarXiv, 2022
Wireless Capsule Endoscopy(WCE) has been widely used for the screening of gastrointestinal(GI) diseases, especially the small intestine, due to its advantages of non-invasive and painless imaging of the entire digestive tract.However, the huge amount of image data captured by WCE makes manual reading a process that requires a huge amount of tasks and ...
arxiv  

Novel aspects of Wnt signaling in intestinal development and cancer [PDF]

open access: yes, 2012
The gastrointestinal tract is a highly specialized organ system responsible for the processing of ingested food, including the uptake of nutrients and the removal of waste products.
Bakker, E.R.M. (Elvira)
core   +8 more sources

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