Results 161 to 170 of about 43,902 (307)

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

Complex demographic, developmental, fitness, and physiological responses of larval eastern hellbenders to elevated water conductivity

open access: yesJournal of Zoology, EarlyView.
Here we explore the effects of elevated water conductivity on larval eastern hellbenders (Cryptobranchus a. alleganiensis), both lethal and sublethal. We found that elevated water conductivity significantly impacts both survival and morphology, though it has limited effects on locomotor performance, stress physiology, and oxidative stress.
S. C. Mathes   +6 more
wiley   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda   +4 more
wiley   +1 more source

Human intestinal and multivisceral transplantation [PDF]

open access: yes, 1994
Abu-Elmagd, K   +8 more
core  

Genetic Diagnoses Among Congenital Anomaly Cases in Europe: Data From the EUROCAT Network

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Surveillance of congenital anomaly prevalence over time can identify new teratogens. Anomalies with a genetic cause are excluded from the monitoring. Objectives We examined temporal changes in the proportion of genetic diagnoses among cases with a congenital anomaly.
Jorieke E. H. Bergman   +23 more
wiley   +1 more source

A Rare Cause of Intestinal Obstruction: Invasive Lobular Breast Carcinoma Metastasizing to the Ileocecal Valve. [PDF]

open access: yesCureus
Douligeris CC   +6 more
europepmc   +1 more source

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