Results 201 to 210 of about 25,379 (250)

Dual‐Module Near‐Infrared Fluorophores Discovery System via Knowledge Transfer

Advanced Science, EarlyView.
This study presents a dual‐module deep learning system for the design of near‐infrared (NIR) fluorophores. A large molecular library is generated and analyzed, leading to the suggestions of promising candidates. The effectiveness of the system is further validated through the synthesis, characterization, and in vivo imaging, demonstrating its potential
Yixin Zhu, Xia Ling, Xianhe Zhang, Chuanjiang Jian, Leilei Shi, Wentao Song, Xiaonan Wang, Bin Liu   +7 more
wiley   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

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Intestinal Transplantation

New England Journal of Medicine, 2009
info:eu-repo/semantics ...
PIRONI, LORIS, Staun M, Van Gossum A.
openaire   +3 more sources

The Intestinal LABs

Antonie van Leeuwenhoek, 2002
The complete gastrointestinal (GI) tract of humans is colonised soon after birth by a myriad of microbial species with a characteristic distribution depending on the location. GI-tract ecology has been experiencing a revival due to the development of molecular techniques, especially those based on 16S RNA (zRNA) genes.
Vaughan, E.E., de Vries, M.C., Zoetendal, E.G., Ben-Amor, K., Akkermans, A.D.L., de Vos, W.M.   +5 more
openaire   +3 more sources

Intestinal stem cells and intestinal organoids

Journal of Genetics and Genomics, 2020
The intestinal epithelium is one of the most rapidly renewing tissues, which is fueled by stem cells at the base of the crypts. Strategies of genetic lineage tracing and organoids, which capture major features of original tissues, are powerful avenues for exploring the biology of intestinal stem cells in vivo and in vitro, respectively. The combination
Qian, Zhao, Jiawei, Guan, Xia, Wang
openaire   +2 more sources

Intestinal Transplantation in Infants with Intestinal Failure

Clinics in Perinatology, 2013
Intestinal failure (IF) occurs when a person's functional intestinal mass is insufficient. Patients with IF are placed on parenteral nutrition (PN) while efforts are made to restore intestinal function through surgical or medical intervention. Patients who fail standard IF therapies may be candidates for intestinal transplantation (IT).
Richard S, Mangus, Girish C, Subbarao
openaire   +2 more sources

Isolated intestinal transplantation for intestinal failure

The American Journal of Gastroenterology, 2000
Parenteral nutrition sustains life in patients with intestinal failure. However, some experience life-threatening complications from parenteral nutrition, and in these individuals intestinal transplantation may be lifesaving.This is a retrospective review of 28 consecutive isolated small bowel transplants performed in eight adults and 20 children ...
D L, Sudan, S S, Kaufman, B W, Shaw, I J, Fox, T M, McCashland, D F, Schafer, S J, Radio, S H, Hinrichs, J A, Vanderhoof, A N, Langnas   +9 more
openaire   +2 more sources

Intestinal transplantation.

Seminars in Pediatric Surgery, 2006
Intestinal transplantation has become a therapeutic option for irreversible benign chronic intestinal failure associated with life-threatening complications of long-term HPN or high risk of death due to the underlying gastrointestinal disease. Four transplant types can be performed: isolated small bowel transplant, multivisceral transplant, combined ...
PINNA, ANTONIO DANIELE, PIRONI, LORIS, Tzakis A.G.   +2 more
openaire   +4 more sources

Intestinal antisepsis

Diseases of the Colon & Rectum, 1965
The role of antibiotics in large bowel surgery was established by experimental studies indicating that antibiotics could protect a colonic anastomosis subjected to unusual stress. A number of different agents were studied to patients to determine which ones significantly altered the bacterial flora of the colon. Clinical studies were conducted with the
openaire   +5 more sources