Results 91 to 100 of about 163,212 (368)

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

Intima–media complex thickness and carotid atherosclerotic plaque formation in Lublin’s population in the context of selected comorbidities

Journal of Ultrasonography, 2018
Introduction: Atherosclerosis (arteriosclerosis) is a chronic arterial disease of the arteries with chronic inflammatory. The pathology of atherosclerosis is complex, and the atherosclerotic process is multi-factorial, not fully understood.
Tomasz Słomka, Anna Drelich-Zbroja, Magdalena Jarząbek, Małgorzata Szczerbo-Trojanowska   +3 more
doaj   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source

Liraglutide improves metabolic parameters and carotid intima-media thickness in diabetic patients with the metabolic syndrome: an 18-month prospective study

Cardiovascular Diabetology, 2016
BackgroundLiraglutide, a GLP-1 analogue, exerts several beneficial non-glycemic effects in patients with type-2 diabetes (T2DM), such as those on body weight, blood pressure, plasma lipids and inflammation markers.
M. Rizzo, A. Rizvi, A. Patti, D. Nikolić, R. V. Giglio, G. Castellino, G. Li Volti, M. Caprio, G. Montalto, V. Provenzano, S. Genovese, A. Ceriello   +11 more
semanticscholar   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source

Separating Geometric Thickness from Book Thickness [PDF]

arXiv, 2001
We show that geometric thickness and book thickness are not asymptotically equivalent: for every t, there exists a graph with geometric thickness two and book thickness >= t.
arxiv  

Low wall shear stress predicts subsequent development of wall hypertrophy in lower limb bypass grafts [PDF]

, 2009
Background: Venous grafts commonly develop myointimal hyperplasia, which can lead to stenoses and, ultimately, with expression of adhesion molecules, lumenal occlusion.
Augst, Chatzizisis, Cheng, Chester, Davies, Davies, Ferziger, Fung, Glagov, Holdsworth, Kassab, Ku, Langlois, Lehoux, Leonard, Long, Malek, McGill, Meyerson, Motwani, Nichols, Salam, Steinman, Suo, Taylor, van Doormal, Walker, Wentzel, Wentzel, Wilson, Wood, Xu, Yusuf, Zureik   +33 more
core   +1 more source

Influence of the arterial elastic component on the response to balloon angioplasty in femoral arteries of a healthy porcine model

Animal Models and Experimental Medicine, EarlyView.
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García, Marina Gil Bernabé, Claudia Pérez‐Martínez, Laura Mola Solà, Luis Duocastella Codina, María Molina Crisol, Alex Gómez Castel, Armando Pérez de Prado   +7 more
wiley   +1 more source

Coexistence of high visceral fat area and sarcopenia is associated with atherosclerotic markers in old‐old patients with diabetes: A cross‐sectional study

Journal of Diabetes Investigation
Aims/Introduction To investigate whether sarcopenic obesity is associated with the progression of atherosclerotic lesions in older patients with diabetes and to identify the obesity components of sarcopenic obesity that best reflect atherosclerosis ...
Motoya Sato, Yoshiaki Tamura, Yuji Murao, Fumino Yorikawa, Yuu Katsumata, So Watanabe, Shugo Zen, Remi Kodera, Kazuhito Oba, Kenji Toyoshima, Yuko Chiba, Atsushi Araki   +11 more
doaj   +1 more source

Relationship between indicators of carotid artery rigidity and cognitive functions in arterial hypertension patients

Сучасні медичні технології, 2019
Purpose of the study. assessment of relationship between the thickness of the intima-media complex, indicators of carotid artery rigidity state and cognitive dysfunction as a marker of brain damage and the study of their prognostic significance in the ...
N. Ya. Dotsenko, S. S. Boev, I. A. Shekhunova, A. V. Molodan, L. V. Gerasimenko, A. Ya. Malynovskaya   +5 more
doaj   +1 more source