Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao +11 more
wiley +1 more source
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta +14 more
wiley +1 more source
Factors for Perceived Helpfulness of Support Sources Among Survivors of Intimate Partner Violence. [PDF]
Cho H, Kim W, Gillis K, Goetz K.
europepmc +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Mental and physical health outcomes among intimate partner violence survivors in Taiwan: A nationwide registry-based case control study. [PDF]
Yeh ST, Li MY, Chen YC.
europepmc +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Inter-generational differentials in perceptions of intimate partner violence in Nigeria. [PDF]
Ntoimo TCI, Adeoye B, Ntoimo LFC.
europepmc +1 more source
Association between food insecurity and intimate partner violence: the role of gendered asset policies. [PDF]
Miller F +4 more
europepmc +1 more source
Assessing the impacts of women's autonomy on their approval of intimate partner violence: a nationwide cross-sectional study. [PDF]
Ibrahim M, Patwary MH, Ahmed A.
europepmc +1 more source

