Results 151 to 160 of about 158,041 (284)

TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha   +9 more
wiley   +1 more source

L’ennemi intime, de Florent-Emilio Siri

open access: yesCahiers d’histoire, 2009
Yassin Temlali
doaj   +1 more source

Electrophysiological diagnosis using the coefficient of variation of R‐R intervals and a point‐of‐care nerve conduction device is highly correlated to the diagnosis of diabetic polyneuropathy using conventional electromyographs

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction While treatment for diabetic polyneuropathy (DPN) is still developing, progress has stagnated. The alignment between pathological neurodegeneration in DPN and patients' subjective symptoms is often low, yet these symptoms are frequently used for diagnosis.
Tatsuhito Himeno   +14 more
wiley   +1 more source

The causal effects of hypothyroidism on cardiovascular disease: Bidirectional and multivariable Mendelian randomization study

open access: yesJournal of Diabetes Investigation, EarlyView.
Our study suggests bidirectional causal associations between hypothyroidism and both coronary artery disease (CAD) and myocardial infarction (MI). Moreover, hypothyroidism contributes to an increased risk of peripheral atherosclerosis (PAS). ABSTRACT Background Whether hypothyroidism and cardiovascular disease (CVD) are causally related remains ...
Xuan Bai, Mengyi Sun, Xu Han
wiley   +1 more source

Collagen organisation in the fibrous joint capsules in the digits of the human hand

open access: yesJournal of Anatomy, EarlyView.
The function of the finger joints is important for daily life. In this review of the literature, we consider the role of collagen and its organization within the fibrous finger joint capsules of the interphalangeal (IP) joints and investigate the relationships between collagen orientation and joint function. Abstract Normal function of the hand and, in
Fiona R. Saunders   +3 more
wiley   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen   +4 more
wiley   +1 more source

CD36 and Its Role in Obesity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia   +5 more
wiley   +1 more source

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