Results 71 to 80 of about 17,074 (256)

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma   +6 more
wiley   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

The Grey Zone of Stakeholder Engagement: Misalignment as a Manifestation of Greyness in Stakeholder Collaboration

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study identifies and conceptualises the grey zone of stakeholder engagement and explores how it manifests in a collaborative context related to the promotion of a circular economy. While prior research on stakeholder engagement has highlighted the positive, value‐creating bright side or the harmful dark side of stakeholder engagement, we ...
Annika Blomberg   +2 more
wiley   +1 more source

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg   +1 more
wiley   +1 more source

Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) TPMT/NUDT15 Pharmacogene Curation Expert Panel (PCEP) conducted a comprehensive review of clinical, laboratory, and computational evidence to determine the clinical function assignments for TPMT and NUDT15 star alleles.
Bailey M. Tibben   +10 more
wiley   +1 more source

A moderated chain mediation model examining the relation between smartphone addiction and intolerance of uncertainty among master's and PhD students

open access: yesHeliyon
The theories of relational regulation and compensatory Internet use suggest that intolerance of uncertainty influences smartphone addiction (SPA), which in turn is influenced by other aspects.
Huake Qiu   +5 more
doaj   +1 more source

The Relationships between Intolerance of Uncertainty and Psychological Well-Being

open access: yesSakarya University Journal of Education, 2017
The aim of this study is to investigate the relationship between intolerance of uncertainty and psychological well-being, and to examine the differences between these two variables in terms of gender, perceived income status, and perceived parental ...
Filiz Mine Geçgin, Ümit Sahranç
doaj   +1 more source

Effects of intolerance of uncertainty on turnover intention in transplantation coordinators: the roles of burnout and grit

open access: yesKorean Journal of Transplantation, 2020
Background : Transplantation coordinators are essential professionals who play a wide range of roles in organ transplantation. Their burnout levels have been shown to be very high due to the significant uncertainty they experience at work.
Suran Lee   +3 more
doaj   +1 more source

Inhibitory Control Tells Only Part of the Story: Reward Sensitivity Moderates the Prospective Link Between the No‐Go P3 and Emerging Eating Pathology in Early Adolescents

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Early adolescence is characterized by the onset of mental health problems, including eating pathology (e.g., body image concerns, restrictive eating). Inhibitory control (IC) and reward sensitivity (RS) are two key traits that have been implicated in the development of eating problems.
Jaron X. Y. Tan, Lisa Brooks, Pan Liu
wiley   +1 more source

The Weight of the Number: Perceptions and Practices Surrounding Expected Body Weight Disclosure in Eating Disorder Treatment

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Expected body weight (EBW) determination is common in eating disorder (ED) treatment, yet no evidence‐based guidelines exist for how to discuss EBWs with patients. Clinicians have previously conceptualized these discussions as therapeutic exposures targeting fear of weight gain.
Agatha A. Laboe   +6 more
wiley   +1 more source

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