Results 51 to 60 of about 3,406,112 (242)

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Syndrome of abdominal hypertension in the fore-cast pancreatogenic peritonitis

Кубанский научный медицинский вестник, 2015
We propose a reliable method of direct measurement of intra-abdominal pressure. Found that all patients with peritonitis pancreatogenic has increased intra-abdominal pressure greater than 15 mm hg. art.
S. V. Avakimyan, V. I. Shaposhnikov, G. K. Karipidi, V. A. Avakimyan, A. M. Manuilov   +4 more
doaj  

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Intra-abdominal Hypertension in Critically Ill Patients in The Intensive Care Unit: Measurement & Early Management

SVU - International Journal of Medical Sciences
Background: intra-abdominal pressure is defined as the pressure inside abdominal cavity which is a closed space. this makes the intra-abdominal pressure changes (even the minimal changes) affect the viscera. the influence of the increased intra-abdominal
Gad Sayed Gad, Ramadan AbdElsalam Ahmed Ali , Zeinab Mustafa Sayed   +2 more
doaj   +1 more source

Intra-abdominal hypertension and abdominal compartment syndrome in patients admitted to the ICU

Annals of Intensive Care, 2020
Background Intra-abdominal hypertension is frequently present in critically ill patients and is an independent predictor for mortality. Risk factors for intra-abdominal hypertension and abdominal compartment syndrome have been widely investigated ...
Marije Smit, Bart Koopman, Willem Dieperink, Jan B. F. Hulscher, H. Sijbrand Hofker, Matijs van Meurs, Jan G. Zijlstra   +6 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Analyzing intra-abdominal pressures and outcomes in patients undergoing emergency laparotomy

Journal of Emergencies, Trauma and Shock, 2010
Background : Studies have documented the impact of intra-abdominal hypertension (IAH) on virtually every organ. However, it still remains strangely underdiagnosed. The aims of the study were to assess, in patients undergoing emergency laparotomy, whether
Khan Shehtaj, Verma Akshay, Ahmad Syed, Ahmad Reyaz   +3 more
doaj  

Correlation between intra-abdominal pressure and pulmonary volumes after superior and inferior abdominal surgery

Clinics, 2014
OBJECTIVE:Patients undergoing abdominal surgery are at risk for pulmonary complications. The principal cause of postoperative pulmonary complications is a significant reduction in pulmonary volumes (FEV1 and FVC) to approximately 65-70% of the predicted ...
Roberto de Cleva, Marianna Siqueira de Assumpção, Flavia Sasaya, Natalia Zuniaga Chaves, Marco Aurelio Santo, Claudia Fló, Adriana C. Lunardi, Wilson Jacob Filho   +7 more
doaj   +1 more source

Mechanical Intestinal Obstruction in a Porcine Model: Effects of Intra-Abdominal Hypertension. A Preliminary Study. [PDF]

PLoS ONE, 2016
INTRODUCTION:Mechanical intestinal obstruction is a disorder associated with intra-abdominal hypertension and abdominal compartment syndrome. As the large intestine intraluminal and intra-abdominal pressures are increased, so the patient's risk for ...
L Correa-Martín, E Párraga, F M Sánchez-Margallo, R Latorre, O López-Albors, R Wise, M L N G Malbrain, G Castellanos   +7 more
doaj   +1 more source