Results 181 to 190 of about 1,686,049 (292)

Ultrasound-guided intra-articular injection therapy. [PDF]

BJA Educ
Al-Ani T, Lupton K.
europepmc   +1 more source

Musculoskeletal health among adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, Volume 68, Issue 12, Page 1671-1689, December 2026.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Christina M Marciniak, Maram Sofiany, Reuel Jalal, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms   +11 more
wiley   +1 more source

Randomized clinical trial comparing intra-articular injection of bone marrow aspirate clot and bone marrow aspirate concentrate in grade 3 and 4 knee osteoarthritis. [PDF]

Stem Cell Res Ther
Lana JF, Pires L, Macedo A, Mainine S, Mosaner T, de Moraes Ferreira Jorge D, Azzini G, da Fonseca LF, Tambeli CH, de Andrade MAP.   +9 more
europepmc   +1 more source

Joining Decision‐Making, Moral Thinking, and Collective Action: Grand Challenges as a Phenomenology of Deliberation

Journal of Management Studies, Volume 63, Issue 8, Page 4737-4763, December 2026.
Abstract This conceptual article argues that the mutual relevance of grand challenges and organization and management studies is best approached phenomenologically. Rather than constituting objects to be theorized or denoting special empirical contexts, grand challenges structure researchers’ attention and shape their interpretations of the processes ...
Alfredo Grattarola, Jean‐Pascal Gond, Stefan Haefliger   +2 more
wiley   +1 more source

A single intra-articular injection of IDO-Gal3 shifts synovial fluid metabolic profiles for up to six weeks in male rats with knee instability. [PDF]

Biochimie
Patterson FM, Cruz CJ, Partain BD, Welhaven H, Urrego Hernández E, Breland A, Griffith JL, Wanchoo A, Cooper JO, Yarrow JF, June RK, Keselowsky BG, Hudalla GA, Allen KD.   +13 more
europepmc   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, Volume 13, Issue 62, 9 November 2026.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Intra-articular injection of allogeneic canine adipose-derived stem cell enriched secretome in dogs undergoing tibial plateau leveling osteotomy: a prospective double-blind and randomized pilot trial. [PDF]

Vet Res Commun
Carrera ALC, Minto BW, Alcântara BM, Previtali DAC, Faustino RCS, Tavares ABL, Doiche DP, Nogueira C, Brunel HSS, Pereira RW, Alievi MM, Dias LGGG, Malard PF.   +12 more
europepmc   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Necrotizing Soft Tissue Infection Caused by <i>Klebsiella pneumoniae</i> After Intra-Articular Injection: A Case Report and Literature Review. [PDF]

Infect Drug Resist
Wang X, Chen J, Gui S, Zhang X, Qian J, Xu X, Fan Z.   +6 more
europepmc   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, Volume 18, Issue 11, Page 1456-1469, November 2026.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source