Results 71 to 80 of about 6,871 (232)

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Efficiency of intraarticular injection of PRP and hyaluronic acid combination in osteoarthritis knee: A systematic review and meta-analysis

Journal of Orthopaedic Reports
Background: Intra-articular injection is a viable option in treatment of osteoarthritis knee, especially for patients who do not tolerate pharmacological oral therapy, when drugs are no longer effective, or for those who want to delay or avoid surgical ...
G. Gopinath
doaj   +1 more source

Anti‐inflammatory and osteogenic effects of transcutaneous electrical nerve stimulation in knee osteoarthritis rats via the regulation of the intestinal microbiota

Animal Models and Experimental Medicine, EarlyView.
Transcutaneous electrical nerve stimulation (TENS) improved knee osteoarthritis (KOA) in rats by regulating interleukin‐1β (IL‐1β), IL‐6, and IL‐8 expressions and the bone morphogenetic protein 2 (BMP‐2)/transforming growth factor β (TGF‐β) signaling pathway.
Yan Sun, Tong Ma, Ran Chen, Lan Shen, Xun Tang, Zhiqiang Shen, Hongbin Zhao   +6 more
wiley   +1 more source

Intra-articular platelet-rich plasma injections versus intra-articular corticosteroid injections for symptomatic management of knee osteoarthritis: systematic review and meta-analysis

BMC Musculoskeletal Disorders, 2021
Background Intra-articular (IA) corticosteroid (CS) injections are the mainstay of treatment for symptomatic management in knee osteoarthritis (OA), particularly in the UK.
Michael McLarnon, Neil Heron
doaj   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Efficacy of Intra-articular Mesenchymal Stem Cell Injections Compared to Intra-articular Corticosteroids in Pain Control for Osteoarthritis of the Knee

, 2020
Many adults suffering with knee pain due to osteoarthritis (OA) rely on intra-articular corticosteroids for pain management. Mesenchymal Stem Cells (MSC) intra-articular injections have emerged as an alternative treatment that may have less side effects ...
Monihan, Tara
core  

The efficacy of intra-articular PRP, ozone and ozone+PRP injections in patients with osteoarthritis [PDF]

, 2018
Osteoarthritis (OA) is the most common form of arthritis and some joints are effected more than others. The prevalence of OA increases with age and it represents the major problem for functional impairment in older patients.
Ellialtioglu, Aysegul, Baeza Noci, José, Yeprem, Lale   +2 more
core   +1 more source

Ultrasound‐Guided Hip Pericapsular, Rectus Femoris Peritendinous, and Iliopsoas Bursa Injections Improve Extra‐articular Post‐arthroscopy Hip Pain

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine the short‐ and medium‐term efficacy of ultrasound‐guided hip pericapsular, rectus femoris peritendinous, and iliopsoas bursa injections with anesthetic and corticosteroid to treat post‐arthroscopy hip pain, and if any operative variables correlated with response likelihood.
Meghan E. Sahr, Hanley Ong, Karthik Krishnan, Shu‐Han Wang, Danyal H. Nawabi, Theodore T. Miller   +5 more
wiley   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Safety of Intra-articular Corticosteroid Injection [PDF]

Radiology, 2020
Matthew Jiang, Keith Lim, Mandana Nikpour   +2 more
openaire   +5 more sources