This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo +40 more
wiley +1 more source
Anatomically-guided Masked Autoencoder with Domain-Adaptive Prompting (AMAP) for multimodal cerebral aneurysm detection and segmentation. [PDF]
Huang M +13 more
europepmc +1 more source
Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li +12 more
wiley +1 more source
Validation and comparison of two commercial OCT systems for in vitro measurement of soft contact lens thickness. [PDF]
Romaguera M +4 more
europepmc +1 more source
Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu +6 more
wiley +1 more source
Firoj Al-Mamun,1– 3 Mohammed A Mamun,1– 3 Moneerah Mohammad ALmerab,4 David Gozal5 1CHINTA Research Bangladesh, Savar, Dhaka, Bangladesh; 2Department of Public Health, University of South Asia, Dhaka, Bangladesh; 3Department of Public Health and ...
Al-Mamun F +3 more
doaj
Knowledge enhancement and full utilization of document information for document-level biomedical relation extraction. [PDF]
Chen X, He L, Liu Y.
europepmc +1 more source
Nanoscale Mapping of the Subcellular Glycosylation Landscape
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter +4 more
wiley +1 more source
Digital coding metamaterials with multi-modulation schemes and beam steering for intra-chip millimeter-wave connectivity. [PDF]
Shen Z, Taravati S, Yan J.
europepmc +1 more source
Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li +15 more
wiley +1 more source

