Results 41 to 50 of about 525,824 (228)

Hybrid Beamforming via the Kronecker Decomposition for the Millimeter-Wave Massive MIMO Systems [PDF]

, 2017
Despite its promising performance gain, the realization of mmWave massive MIMO still faces several practical challenges. In particular, implementing massive MIMO in the digital domain requires hundreds of RF chains matching the number of antennas ...
Huang, Kaibin, Lau, Vincent K. N., Li, Xiaofan, Xia, Bin, Zhang, Sha, Zhu, Guangxu   +5 more
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

A hybrid TIM-NOMA scheme for the SISO Broadcast Channel [PDF]

, 2015
Future mobile communication networks will require enhanced network efficiency and reduced system overhead due to their user density and high data rate demanding applications of the mobile devices.
Johnson, Oliver, Kalokidou, Vaia, Piechocki, Robert   +2 more
core   +7 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Validation of automated artificial intelligence segmentation of optical coherence tomography images.

PLoS ONE, 2019
PurposeTo benchmark the human and machine performance of spectral-domain (SD) and swept-source (SS) optical coherence tomography (OCT) image segmentation, i.e., pixel-wise classification, for the compartments vitreous, retina, choroid, sclera.MethodsA ...
Peter M Maloca, Aaron Y Lee, Emanuel R de Carvalho, Mali Okada, Katrin Fasler, Irene Leung, Beat Hörmann, Pascal Kaiser, Susanne Suter, Pascal W Hasler, Javier Zarranz-Ventura, Catherine Egan, Tjebo F C Heeren, Konstantinos Balaskas, Adnan Tufail, Hendrik P N Scholl   +15 more
doaj   +1 more source

Efficient Micro-Mobility using Intra-domain Multicast-based Mechanisms (M&M) [PDF]

, 2001
One of the most important metrics in the design of IP mobility protocols is the handover performance. The current Mobile IP (MIP) standard has been shown to exhibit poor handover performance. Most other work attempts to modify MIP to slightly improve its
Bhaskara, Ganesha, Helmy, Ahmed, Jaseemuddin, Muhammad   +2 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

An improved cross-domain sequential recommendation model based on intra-domain and inter-domain contrastive learning

Complex & Intelligent Systems
Cross-domain recommendation aims to integrate data from multiple domains and introduce information from source domains, thereby achieving good recommendations on the target domain.
Jianjun Ni, Tong Shen, Yonghao Zhao, Guangyi Tang, Yang Gu   +4 more
doaj   +1 more source

Caenorhabditis briggsae recombinant inbred line genotypes reveal inter-strain incompatibility and the evolution of recombination. [PDF]

PLoS Genetics, 2011
The nematode Caenorhabditis briggsae is an emerging model organism that allows evolutionary comparisons with C. elegans and exploration of its own unique biological attributes. To produce a high-resolution C.
Joseph A Ross, Daniel C Koboldt, Julia E Staisch, Helen M Chamberlin, Bhagwati P Gupta, Raymond D Miller, Scott E Baird, Eric S Haag   +7 more
doaj   +1 more source